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NHERF-2 Antibody

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Western Blot: NHERF-2 Antibody [NBP1-91569] - Titration: 1.0 ug/ml Positive Control: Rat Brain.

Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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NHERF-2 Antibody Summary

Description
The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
Immunogen
Synthetic peptide directed towards the N terminal of human Slc9a3r2. Peptide sequence RLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGV. The peptide sequence for this immunogen was taken from within the described region.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLC9A3R2
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for NHERF-2 Antibody

  • E3KARP
  • Na(+)/H(+) exchange regulatory cofactor NHE-RF2
  • NHE3RF2
  • NHERF2MGC104639
  • NHERF-2NHE3 kinase A regulatory protein E3KARP
  • OCTS2
  • SIP-1SRY-interacting protein 1
  • sodium/hydrogen exchanger
  • Sodium-hydrogen exchanger regulatory factor 2
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatoryfactor 2
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
  • Solute carrier family 9 isoform A3 regulatory factor 2
  • TKA-1SIP1
  • Tyrosine kinase activator protein 1

Background

NHERF-2 is a scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SLC9A3R2
Uniprot