ELISA: Mouse NF-L ELISA Kit (Colorimetric) [NBP2-80299] - Samples were spiked with high concentrations of Mouse NF-L and diluted with Reference Standard & Sample Diluent to produce samples with values within the range ...read more
Storage of components varies. See protocol for specific instructions.
Kit Components
Components
Biotinylated Detection Ab Diluent
Concentrated Biotinylated Detection Ab (100x)
Concentrated HRP Conjugate (100x)
Concentrated Wash Buffer (25X)
HRP Conjugate Diluent
Micro ELISA Plate (Dismountable)
Plate Sealer
Product Manual
Reference Standard
Sample Diluent
Stop Solution
Substrate Reagent
Alternate Names for Mouse NF-L ELISA Kit (Colorimetric)
68 kDa neurofilament protein
CMT2E
NEFL
neurofilament protein, light chain
neurofilament subunit NF-L
Neurofilament triplet L protein
neurofilament, light polypeptide
neurofilament-light
NF68
NF68FLJ53642
NFL
NF-L
NFLlight polypeptide 68kDa
Background
Neurofilaments are 10nm intermediate filament proteins located in vertebrate neurons, which regulate axonal diameter. They are composed predominantly of the three major neurofilament proteins: NF-Light, NF-Medium and NF-Heavy. NF-L is the light or low molecular weight polypeptide, and it runs on SDS-PAGE gels at about 68kDa, with some size variation in across species.
Antibodies to NF-L may be used to identify NF-L in neurons and to study neuronal processes in tissue sections and/or culture. NF-L antibodies can also be used to study microfilament accumulations seen in many neurological diseases, such as Lou Geri's disease or Alzheimer's disease.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.
We have publications tested in 1 application: ELISA.
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Berthiaume A, Reda S, Johnston J et al. ATH-1105, a Small Molecule Positive Modulator of HGF/MET, is Neuroprotective and Preserves Motor and Nerve Function in a TDP-43 Mouse Model of ALS Cell Reports Medicine 2023-02-22 (ELISA)
ELISA
Jalnapurkar B, Le D, Shainin W et al. A deep-learning-based screening platform in aging-relevant human motor neurons to identify therapeutic compounds for amyotrophic lateral sclerosis bioRxiv 2023-11-22 (ELISA)
ELISA
Review for NF-L ELISA Kit (NBP2-80299) (1)
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Average Rating: 5 (Based on 1 review)
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reviewed by: Verified Customer
04/17/2024
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Summary
Sample Tested
Blood plasma
Lot
ZD22F4JJ6187
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