NF-L Products

Description

Neurofilaments are 10nm intermediate filament proteins located in vertebrate neurons, which regulate axonal diameter. They are composed predominantly of the three major neurofilament proteins: NF-Light, NF-Medium and NF-Heavy. NF-L is the light or low molecular weight polypeptide, and it runs on SDS-PAGE gels at about 68kDa, with some size variation in across species.

Antibodies to NF-L may be used to identify NF-L in neurons and to study neuronal processes in tissue sections and/or culture. NF-L antibodies can also be used to study microfilament accumulations seen in many neurological diseases, such as Lou Geri's disease or Alzheimer's disease.

Bioinformatics

Entrez	18039 Mouse 281348 Bovine 4747 Human 83613 Rat
Uniprot	NM_006158 Human NP_006149.2 Human P02547 Porcine P02548 Bovine P07196 Human
Product By Gene ID	4747
Alternate Names	68 kDa neurofilament protein neurofilament protein, light chain neurofilament subunit NF-L Neurofilament triplet L protein neurofilament, light polypeptide neurofilament-light NF68FLJ53642 NF-L NFLlight polypeptide 68kDa

Research Areas for NF-L

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Cellular Markers
Cytoskeleton Markers
Neurodegeneration
Neurofilaments
Neuronal Cell Markers
Neuroscience