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Neprilysin-2/MMEL1 Antibody

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Immunohistochemistry: Neprilysin-2/MMEL1 Antibody [NBP1-92125] - Staining of human testis shows moderate positivity in seminiferus duct cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Neprilysin-2/MMEL1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLD
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MMEL1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Neprilysin-2/MMEL1 Protein (NBP1-92125PEP)
Publications
Read Publication using NBP1-92125.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (80%). Reactivity reported in scientific literature (PMID: 20796280)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Neprilysin-2/MMEL1 Antibody

  • EC 3.4.24
  • EC 3.4.24.11
  • MELL1
  • membrane metallo-endopeptidase-like 1
  • Membrane metallo-endopeptidase-like 2MGC119455
  • MGC119454
  • MMEL1
  • MMEL2
  • NEP2
  • NEP2(m)
  • NEPIIMGC119456
  • Neprilysin II
  • Neprilysin2
  • Neprilysin-2
  • NL2
  • NL2NL1
  • SEP
  • soluble secreted endopeptidase
  • zinc metallopeptidase

Background

MMELL1 is encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Neprilysin-2/MMEL1 Antibody (NBP1-92125)(1)


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Bioinformatics

Gene Symbol MMEL1