NAIP Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Neuronal apoptosis inhibitory protein (NAIP; also Baculoviral IAP repeat-containing protein 1) is a 160 kDa member of the inhibitor of apoptosis family of proteins (also known as BIRC proteins). Human NAIP is 1403 amino acids (aa) in length. It contains three distinct regions: an N-terminal cluster of three baculoviral inhibitory repeat (BIR) domains, a central nucleotide binding oligomerization domain (NOD), and a C-terminal leucine-rich repeat (LRR) domain. Human NAIP shares 68% aa identity with mouse NAIP. NAIP is expressed in motor neurons, but not in sensory neurons. It is also expressed in the liver, placenta and to a lesser extent in the spinal cord. NAIP prevents motor neuron apoptosis, and defects in NAIP have been found in individuals with spinal muscular atrophy.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.

Showing Publications 1 - 3 of 3.

Publications using AF829	Applications	Species
Vassina EM, Yousefi S, Simon D, Zwicky C, Conus S, Simon HU cIAP-2 and survivin contribute to cytokine-mediated delayed eosinophil apoptosis. Eur. J. Immunol., 2006-07-01;36(7):1975-84. 2006-07-01 [PMID: 16761316] (Western Blot, Human)	Western Blot	Human
Kevin M. Wright, Michael W. Linhoff, Patrick Ryan Potts, Mohanish Deshmukh Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis The Journal of Cell Biology 10/25/2004 [PMID: 15504912]
Altznauer F, Martinelli S, Yousefi S, Thurig C, Schmid I, Conway EM, Schoni MH, Vogt P, Mueller C, Fey MF, Zangemeister-Wittke U, Simon HU Inflammation-associated cell cycle-independent block of apoptosis by survivin in terminally differentiated neutrophils. J. Exp. Med., 2004-05-17;199(10):1343-54. 2004-05-17 [PMID: 15148334] (Human)		Human

Array AF829

• NAIP Antibodies
• NAIP ELISA Kit
• NAIP Proteins