MuRF1/TRIM63 Antibody

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.

Showing Publications 1 - 2 of 2.

Publications using NBP1-54939	Applications	Species
Saroul N, Tardif N, Pereira B et al. Conditioned Media from Head and Neck Cancer Cell Lines and Serum Samples from Head and Neck Cancer Patients Drive Catabolic Pathways in Cultured Muscle Cells Cancers 2023-03-19 [PMID: 36980729] (WB, Human)	WB	Human
Tardif N, Klaude M, Lundell L et al. Autophagic-lysosomal pathway is the main proteolytic system modified in the skeletal muscle of esophageal cancer patients. Am J Clin Nutr. 2013-12-01 [PMID: 24108784] (WB, Human)	WB	Human

Images	Ratings	Applications	Species	Date	Details
	4 reviewed by: Verified Customer	WB	Human	12/23/2014	View Summary Application Western Blot Sample Tested See PMID 24108784 Species Human

Array NBP1-54939

• MuRF1/TRIM63 Antibodies
• MuRF1/TRIM63 Proteins