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MSX1 Antibody (801601) [Unconjugated]

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MSX1 was detected in immersion fixed paraffin-embedded sections of human ovary using Mouse Anti-Human MSX1 Monoclonal Antibody (Catalog # MAB5045) at 15 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counter-stained with hematoxylin (blue). Specific staining was localized to nuclei. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
MSX1 was detected in immersion fixed paraffin-embedded sections of human ovary using Mouse Anti-Human MSX1 Monoclonal Antibody (Catalog # MAB5045) at 15 µg/mL overnight at 4 °C. Before incubation with the primary ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
801601
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB5045-SP
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MSX1 Antibody (801601) [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human MSX1
Met1-Thr165
Accession # P28360
Specificity
Detects human MSX1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human MSX2 is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
MSX1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 8-25 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MSX1 Antibody (801601) [Unconjugated]

  • Homeobox protein Hox-7
  • homeobox protein MSX-1
  • HOX7
  • HOX7homeobox 7
  • HYD1
  • HYD1msh homeobox homolog 1 (Drosophila)
  • msh (Drosophila) homeo box homolog 1 (formerly homeo box 7)
  • msh homeo box 1
  • msh homeobox 1
  • Msh homeobox 1-like protein
  • msh homeobox homolog 1
  • MSX1
  • OFC5
  • STHAG1

Background

MSX1 (Msh homeobox homology 1) is a member of the muscle segment homoebox gene family. MSX1 is involved in limb-pattern formation, craniofacial development, odontogenesis, and tumor growth inhibition. MSX1 functions as a transcriptional repressor. MSX1 has been shown to interact with the linker histone, H1B, and repress transcription of the MyoD promoter. Chromosomal abnormalities involving MSX1 have been associated with the Wolf-Hirschhorn syndrome characterized by heart defects and mental retardation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MSX1
Uniprot