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MSH6 Antibody [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IP (-)
Clonality
Polyclonal
Host
Goat
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-328AF350
Alexa Fluor 405
NB100-328AF405
Alexa Fluor 488
NB100-328AF488
Alexa Fluor 532
NB100-328AF532
Alexa Fluor 594
NB100-328AF594
Alexa Fluor 647
NB100-328AF647
Alexa Fluor 700
NB100-328AF700
Alexa Fluor 750
NB100-328AF750
Allophycocyanin
NB100-328APC
Biotin
NB100-328B
CoraFluor 1
NB100-328CL1
DyLight 350
NB100-328UV
DyLight 405
NB100-328V
DyLight 488
NB100-328G
DyLight 550
NB100-328R
DyLight 594
NB100-328DL594
DyLight 650
NB100-328C
DyLight 680
NB100-328FR
DyLight 755
NB100-328IR
FITC
NB100-328F
HRP
NB100-328H
Janelia Fluor 525
NB100-328JF525
Janelia Fluor 549
NB100-328JF549
Janelia Fluor 585
NB100-328JF585
Janelia Fluor 635
NB100-328JF635
Janelia Fluor 669
NB100-328JF669
PE
NB100-328PE
PerCP
NB100-328PCP
Unconjugated
NB100-328
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MSH6 Antibody [Janelia Fluor® 646] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 350 and 400 of human MutS homolog 6 using the numbering given in entry NP_000170.1 (GeneID 2956).
Localization
Nuclear
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
MSH6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for MSH6 Antibody [Janelia Fluor® 646]

  • DNA mismatch repair protein Msh6
  • G/T mismatch-binding protein
  • GTBPHNPCC5
  • GTMBP
  • hMSH6
  • HSAP
  • mutS (E. coli) homolog 6
  • mutS homolog 6 (E. coli)
  • MutS-alpha 160 kDa subunit
  • p160
  • sperm-associated protein

Background

MSH6 is a mismatch-repair protein. It plays a role in tumor suppression. Genomic mutations in MSH6 predispose to the hereditary non-polyposis colorectal cancer (HNPCC) syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for MSH6 Antibody (NB100-328JF646). (Showing 1 - 1 of 1 FAQ).

  1. I am testing a mouse sample with human xenograft for GBM and I am looking for an MSH6 Antibody that will only detect the human cells.
    • Currently, we have no validation that any of our MSH6 antibodies will not cross react with mouse. All of our MSH6 Antibodies are raised against Human MSH6 so we have checked the % homology with mouse MSH6 which has come to be 85%. As 85% is very high, the chances of the antibody detecting the mouse tissue as well as the human tissue are high.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol MSH6