Home » Mrc2 » Mrc2 Antibodies » Mrc2 Antibody
Novus Biologicals products are now on bio-techne.com

Mrc2 Antibody

 (3 Publications)
 See All Related
Submit a Review

Images

 
(
Enlarge)
Western blot shows lysates of mouse heart, lung, and kidney tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Mouse Mrc2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4789) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Mrc2 at approximately 170-180 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.
Western blot shows lysates of mouse heart, lung, and kidney tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Mouse Mrc2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4789) followed by ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Sheep
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
AF4789-SP
Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Novus Biologicals, part of Bio-Techne, offers 100% Guarantee

Mrc2 Antibody Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Mrc2
Ala31-Ala1413
Accession # AAI16643
Specificity
Detects mouse Mrc2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 25% cross‑reactivity with recombinant human Mrc2 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Sheep
Gene
MRC2
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
Publications
Read Publications using
AF4789 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mrc2 Antibody

  • CD280 antigen
  • CD280
  • CD280C-type mannose receptor 2
  • CLEC13E
  • CLEC13EUPAR-associated protein
  • Endo180
  • ENDO180C-type lectin domain family 13 member E
  • Endocytic receptor 180
  • KIAA0709FLJ35911
  • Macrophage mannose receptor 2
  • mannose receptor, C type 2
  • Mrc2
  • uPARAP
  • UPARAPendocytic receptor (macrophage mannose receptor family)
  • urokinase plasminogen activator receptor-associated protein
  • Urokinase receptor-associated protein
  • Urokinase-type plasminogen activator receptor-associated protein

Background

Mrc2 (macrophage mannose receptor 2; also uPARAP/Endo180) is a 180 kDa member of the mannose receptor family. It is found on fibroblasts, macrophages and endothelial cells. Mrc2 binds and internalizes glycoproteins plus collagen types I and IV. Mouse Mrc2 is a type I transmembrane glycoprotein that is 1479 amino acids (aa) in length. It possesses a 1383 aa extracellular domain (ECD) (aa 31‑1479) and a short 45 aa cytoplasmic tail. The ECD contains eight C‑type lectin domains plus one fibronectin type II domain (aa 181‑229) that binds collagen. There are two splice variants, one which shows an eight aa substitution for aa 173‑1479, and a second that shows a 72 aa substitution for aa 982‑1479. Over aa 311‑413, mouse Mrc2 shares 91% and 97% aa identity with human and rat Mrc2, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

uPAR [HRP]
DUP00
N/A uPAR [HRP]
N/A uPAR [HRP]
(44 Publications)
Species: Hu
Applications: ELISA
u-Plasminogen
Activator/Urokinase [ ...
1310-SE
Enzyme Activity u-Plasminogen Activator/Urokinase [Unconjugated]
(14 Publications)
Species: Hu
Applications: EnzAct
Integrin alpha
2/CD49b Antibody (HAS ...
MAB1233
Immunocytochemistry Integrin alpha 2/CD49b Antibody (HAS3) [Unconjugated]
Flow Cytometry Integrin alpha 2/CD49b Antibody (HAS3) [Unconjugated]
(7 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, ICC, IP
PRAP1 Antibody
NBP1-80633
Immunohistochemistry-Paraffin PRAP1 Antibody
(2 Publications)
Species: Hu
Applications: IHC, IHC-P
Fibronectin
Antibody - BSA Free
NBP1-91258
Western Blot Fibronectin Antibody - BSA Free
Western Blot Fibronectin Antibody - BSA Free
Western Blot Fibronectin Antibody - BSA Free
(11 Reviews)
(56 Publications)
Species: Bv, Ca, Eq, Fe, Hu, Mu, Po, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB
DEC-205/CD205
Antibody
AF5975
Western Blot DEC-205/CD205 Antibody
(1 Review)
Species: Mu
Applications: WB
MMP-13 [HRP]
DM1300
N/A MMP-13 [HRP]
N/A MMP-13 [HRP]
(34 Publications)
Species: Hu
Applications: ELISA
MMP-14/MT1-MMP
Antibody (128527) [Un ...
MAB9181
Flow Cytometry MMP-14/MT1-MMP Antibody (128527) [Unconjugated]
Immunohistochemistry MMP-14/MT1-MMP Antibody (128527) [Unconjugated]
(11 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, IHC, IP, WB
MMR/CD206/Mannose
Receptor Antibody [Un ...
AF2535
Immunohistochemistry MMR/CD206/Mannose Receptor Antibody [Unconjugated]
Western Blot MMR/CD206/Mannose Receptor Antibody [Unconjugated]
Immunohistochemistry MMR/CD206/Mannose Receptor Antibody [Unconjugated]
(2 Reviews)
(192 Publications)
Species: Mu
Applications: CyTOF-ready, Flow, IHC, WB
NOD2 Antibody
(2D9) - BSA Free
NB100-524
Flow Cytometry NOD2 Antibody (2D9) - BSA Free
Flow Cytometry NOD2 Antibody (2D9) - BSA Free
Immunohistochemistry-Frozen NOD2 Antibody (2D9) - BSA Free
(1 Review)
(26 Publications)
Species: Hu, Mu
Applications: Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
HLA DQ/DR/DP
Antibody (HLA-Pan/296 ...
NBP2-79843
Protein Array HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free
Immunocytochemistry/ Immunofluorescence HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free
Western Blot HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free
Species: Hu
Applications: CyTOF-ready, ELISA, Flow, ICC/IF, IHC, IHC-P, PA, WB
CTLA-4
[Unconjugated]
7268-CT
Bioactivity CTLA-4 [Unconjugated]
(3 Publications)
Species: Hu
Applications: BA
MMP-2 [HRP]
MMP200
N/A MMP-2 [HRP]
N/A MMP-2 [HRP]
(101 Publications)
Species: Ca, Hu, Mu, Po, Rt
Applications: ELISA
CD31/PECAM-1
Antibody [Unconjugate
AF3628
Immunohistochemistry CD31/PECAM-1 Antibody [Unconjugated]
Flow Cytometry CD31/PECAM-1 Antibody [Unconjugated]
Immunohistochemistry CD31/PECAM-1 Antibody [Unconjugated]
(6 Reviews)
(505 Publications)
Species: Hu, Mu, Rt
Applications: CyTOF-ready, Flow, ICC, IHC, Simple Western, WB
TGF-beta RI/ALK-5
Antibody [Unconjugate ...
AF3025
Western Blot TGF-beta RI/ALK-5 Antibody [Unconjugated]
Immunocytochemistry TGF-beta RI/ALK-5 Antibody [Unconjugated]
Western Blot TGF-beta RI/ALK-5 Antibody [Unconjugated]
(16 Publications)
Species: Hu
Applications: ELISA, ICC, WB
Mrc2 Antibody
AF4789
Mrc2 Antibody
Species: Mu
Applications: WB

Publications for Mrc2 Antibody (AF4789)(3)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: Immunohistochemistry, Western Blot.


Filter By Application
Immunohistochemistry
(1)
Western Blot
(1)
All Applications
Filter By Species
Mouse
(1)
All Species

Reviews for Mrc2 Antibody (AF4789) (0)

There are no reviews for Mrc2 Antibody (AF4789). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Mrc2 Antibody (AF4789) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Mrc2 Products

Blogs on Mrc2

There are no specific blogs for Mrc2, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

  PDF SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Mrc2 Antibody and receive a gift card or discount.


Bioinformatics

Gene Symbol MRC2
Uniprot