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mGluR3 Antibody (440511) [PE/Cy7]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
440511
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Cy7

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mGluR3 Antibody (440511) [PE/Cy7] Summary

Immunogen
Hek293 cells transfected with human mGLUR3
Accession # Q14832
Specificity
Detects human mGLUR3 in direct ELISAs.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for mGluR3 Antibody (440511) [PE/Cy7]

  • GLUR3
  • glutamate receptor, metabotropic 3
  • GPRC1C
  • GPRC1Cglutamate metabotropic receptor 3
  • GRM3
  • mGlu3
  • mGluR3
  • MGLUR3metabotropic glutamate receptor 3

Background

The Metabotropic Glutamate Receptor GRM3 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Metabotropic glutamate receptor Group II includes the GRM2 and GRM3 receptors that are linked to inhibition of the cyclic AMP signaling cascade. GRM3 has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain, embryo, fetal lung/testis/B-cell, nerve, placenta, prostate, and vessel libraries. Caution: GLUR3 refers to Ionotropic Glutamate Receptor 3, not to Metabotropic Glutamate Receptor 3 (mGLUR3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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