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mGluR1 Antibody (1059503) [Unconjugated]

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mGluR1 was detected in immersion fixed paraffin-embedded sections of Human Hippocampus using Mouse Anti-Human mGluR1 Monoclonal Antibody (Catalog # MAB48362) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to plasma membrane and cytoplasm in neurons. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.
mGluR1 was detected in immersion fixed paraffin-embedded sections of Human Hippocampus using Mouse Anti-Human mGluR1 Monoclonal Antibody (Catalog # MAB48362) at 5 µg/mL for 1 hour at room temperature followed ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
1059503
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB48362-SP
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mGluR1 Antibody (1059503) [Unconjugated] Summary

Immunogen
Synthetic peptide
Accession # P42261
Specificity
Detects mouse GluR1 in direct ELISA.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-25 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for mGluR1 Antibody (1059503) [Unconjugated]

  • glutamate receptor, metabotropic 1
  • GPRC1A
  • GRM1
  • GRM1A
  • metabotropic glutamate receptor 1
  • mGluR1
  • MGLUR1A
  • MGLUR1GPRC1AmGlu1

Background

GluR1 is a 4-transmembrane protein that belongs to the glutamate-gated ion channel family. It is one of four AMPA receptor subunits that form a functional heterotetrameric glutamate receptor. GluR1 only interacts with GluR2. In addition to constitutive phosphorylation on a key serine in the C-terminal extracellular region, neurotransmitter-induced phosphorylation of another key serine by CaMKII leads to a potentiation of glutamate-mediated current.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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mGluR1 Antibody
(1059503) [Unconjugat ...
MAB48362
mGluR1 Antibody (1059503) [Unconjugated]
Species: Hu
Applications: IHC

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