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MERIT40/HSPC142 Antibody

Images

 
Western Blot: MERIT40/HSPC142 Antibody [NBP2-58126] - Western blot analysis in human cell line RT-4 and human cell line U-251 MG.
Immunocytochemistry/ Immunofluorescence: MERIT40/HSPC142 Antibody [NBP2-58126] - Staining of human cell line A-431 shows localization to nuclear bodies.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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MERIT40/HSPC142 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADDGSLNTSGAGPKSWQVPPPAPEVQIRTPRVNCPEKVIICL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BABAM1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Western Blot 0.04-0.4 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
MERIT40/HSPC142 Recombinant Protein Antigen (NBP2-58126PEP)

Reactivity Notes

Mouse 80%, Rat 80%

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for MERIT40/HSPC142 Antibody

  • BABAM1
  • BRISC and BRCA1 A complex member 1
  • C10orf62
  • C19orf62
  • chromosome 19 open reading frame 62
  • FLJ20571
  • HSPC142
  • mediator of Rap80 interactions and targeting 40 kDa
  • Mediator of RAP80 interactions and targeting subunit of 40 kDa
  • MERIT40
  • MERIT40BRCA1-A complex subunit MERIT40
  • NBA1
  • NBA1BRISC and BRCA1 A complex member
  • new component of the BRCA1 A complex
  • New component of the BRCA1-A complex
  • new component of the BRCAA1 A complex

Background

HSPC142 is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRC

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol BABAM1