LZTR2 Antibody - BSA Free Summary
Immunogen |
Antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human LZTR2. The immunogen is located within the last 50 amino acids of LZTR2. Amino Acid Squence: TSLNRPNRLAQRRYPTQP |
Predicted Species |
Bovine (100%), Rabbit (94%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
SEC16B |
Purity |
Peptide affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA 1:100 - 1:2000
- Immunocytochemistry/ Immunofluorescence 20 ug/mL
- Immunohistochemistry 5 ug/mL
- Immunohistochemistry-Paraffin 5 ug/mL
- Western Blot 1 ug/mL
|
Control Peptide |
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Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.02% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Peptide affinity purified |
Alternate Names for LZTR2 Antibody - BSA Free
Background
LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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