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Integrin alpha L/CD11a Antibody (I21/7) [Biotin]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, IHC, IP, ICC/IF
Clone
I21/7
Clonality
Monoclonal
Host
Rat
Conjugate
Biotin
Concentration
0.5 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
FITC
NBP1-27871
Unconjugated
NBP1-27870
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-27870
Azide and BSA Free
NBP1-27870
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Integrin alpha L/CD11a Antibody (I21/7) [Biotin] Summary

Immunogen
Whole BW5147 cells
Specificity
Mouse/Human CD11a
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
ITGAL
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry <= 1 ug/10^6 cells
  • Immunocytochemistry
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:100-1:2000
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Notes

Protect conjugated forms from light.

Alternate Names for Integrin alpha L/CD11a Antibody (I21/7) [Biotin]

  • CD11 antigen-like family member A
  • CD11a antigen
  • CD11a
  • CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide
  • Integrin alpha L
  • integrin alpha-L
  • integrin gene promoter
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide)
  • ITGAL
  • Leukocyte adhesion glycoprotein LFA-1 alpha chain
  • Leukocyte function-associated molecule 1 alpha chain
  • LFA-1 alpha
  • LFA-1
  • LFA1A
  • LFA-1A
  • Ly-15
  • Ly-21
  • lymphocyte function-associated antigen 1

Background

The monoclonal antibody I21/7 reacts with the alpha subunit of mouse CD11a, also known as Leukocyte Function-associated Antigen-1 (LFA-1) and a member of the integrin family of cell adhesion molecules. (1, 2) The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow. (2) CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Co-stimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1. (1, 2)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Integrin alpha L/CD11a Antibody (I21/7) [Biotin]
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Bioinformatics

Gene Symbol ITGAL