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Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free

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Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) [NBP1-27870] - BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD11a-UNLB followed by Mouse Anti-Rat IgG2a-FITC.
Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) [NBP1-27870] - BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD11a-UNLB followed by Mouse Anti-Rat IgG2a-FITC.
Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) [NBP1-27870] - Analysis using the Biotin conjugate of NBP1-27870. Multiple staining of BALB/c splenocytes.
Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) [NBP1-27870] - Analysis using the FITC conjugate of NBP1-27870. Double staining of BALB/c spleen cells with rat antimouse CD11a-R-PE and rat anti-mouse ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, B/N
Clone
I21/7
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
0.5 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Biotin
NBP1-27872
FITC
NBP1-27871
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Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free Summary

Immunogen
Whole BW5147 cells
Specificity
Mouse/Human CD11a
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
ITGAL
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Block/Neutralize
  • Flow Cytometry 1:10 - 1:1000
Application Notes
Although not tested this antibody may be useful for Immunoblotting.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
0.1M BBS (pH 8.2)
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free

  • CD11 antigen-like family member A
  • CD11a antigen
  • CD11a
  • CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide
  • Integrin alpha L
  • integrin alpha-L
  • integrin gene promoter
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide)
  • ITGAL
  • Leukocyte adhesion glycoprotein LFA-1 alpha chain
  • Leukocyte function-associated molecule 1 alpha chain
  • LFA-1 alpha
  • LFA-1
  • LFA1A
  • LFA-1A
  • Ly-15
  • Ly-21
  • lymphocyte function-associated antigen 1

Background

The monoclonal antibody I21/7 reacts with the alpha subunit of mouse CD11a, also known as Leukocyte Function-associated Antigen-1 (LFA-1) and a member of the integrin family of cell adhesion molecules. (1, 2) The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow. (2) CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Co-stimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1. (1, 2)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ITGAL