Indoleamine 2,3-dioxygenase/IDO Antibody (BLR040F) Summary
Additional Information |
Recombinant Monoclonal Antibody. |
Immunogen |
Recombinant protein representing Human IDO1 |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
IDO1 |
Purity |
Antigen Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunoprecipitation 15 ul/1mg lysate
- Western Blot 1:1000
|
Packaging, Storage & Formulations
Storage |
Store at 2 - 8 C / 1 year from date of receipt |
Buffer |
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA |
Preservative |
0.09% Sodium Azide |
Purity |
Antigen Affinity-purified |
Notes
This Product sold under License from Bethyl Laboratories, Inc.
Alternate Names for Indoleamine 2,3-dioxygenase/IDO Antibody (BLR040F)
Background
Indoleamine 2,3-dioxygenase (IDO1) is a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. IDO1 acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. It is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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