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Indoleamine 2,3-dioxygenase/IDO Antibody (BLR040F)

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Western Blot: Indoleamine 2,3-dioxygenase/IDO Antibody (BLR040F) [NBP2-76408] - Detection of human IDO1 by WB of HeLa treated with IFN-gamma (+) or mock treated (-). Antibody: Rabbit anti-IDO1 recombinant monoclonal ...read more
Western Blot: Indoleamine 2,3-dioxygenase/IDO Antibody (BLR040F) [NBP2-76408] - Detection of human IDO1 by WB of immunoprecipitates from HeLa lysate treated with IFN-gamma. Antibodies: Rabbit anti-IDO1 recombinant ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clone
BLR040F
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Indoleamine 2,3-dioxygenase/IDO Antibody (BLR040F) Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Recombinant protein representing Human IDO1
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
IDO1
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunoprecipitation 15 ul/1mg lysate
  • Western Blot 1:1000

Packaging, Storage & Formulations

Storage
Store at 2 - 8 C / 1 year from date of receipt
Buffer
Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA
Preservative
0.09% Sodium Azide
Purity
Antigen Affinity-purified

Notes

This Product sold under License from Bethyl Laboratories, Inc.

Alternate Names for Indoleamine 2,3-dioxygenase/IDO Antibody (BLR040F)

  • 3dioxygenase
  • EC 1.13.11.52
  • IDO
  • IDO1
  • IDOIDO-1
  • INDO
  • INDOindole 2,3-dioxygenase
  • Indoleamine 2
  • indoleamine 2,3-dioxygenase 1
  • Indoleamine 2,3-dioxygenase
  • indoleamine-pyrrole 2,3 dioxygenase
  • Indoleamine-pyrrole 2,3-dioxygenase

Background

Indoleamine 2,3-dioxygenase (IDO1) is a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. IDO1 acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. It is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IDO1