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IL-18/IL-1F4 Antibody (74801) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, CyTOF-ready, Flow, KO
Clone
74801
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC646U-100UG
Alexa Fluor 405
IC646V-100UG
Alexa Fluor 488
IC646G-100
Alexa Fluor 532
FAB646X
Alexa Fluor 594
IC646T-100UG
Alexa Fluor 647
IC646R-100UG
Alexa Fluor 700
IC646N-100UG
Alexa Fluor 750
IC646S-100UG
Allophycocyanin
FAB646A
Biotin
FAB646B
DyLight 350
FAB646D
DyLight 488
FAB646K
DyLight 550
FAB646L
DyLight 594
FAB646M
DyLight 650
FAB646W
DyLight 680
FAB646Y
DyLight 755
FAB646Z
FITC
FAB646F
HRP
FAB646H
Janelia Fluor 525
FAB646JF525
Janelia Fluor 549
FAB646I
Janelia Fluor 585
FAB646JF585
Janelia Fluor 635
FAB646JF635
Janelia Fluor 646
FAB646J
Janelia Fluor 669
FAB646JF669
PerCP
FAB646C
Phycoerythrin
IC646P
Unconjugated
MAB646
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB646
Carrier Free
MAB646
Carrier Free
MAB646-SP
Carrier Free
IC646P
Carrier Free
IC646S-100UG
Carrier Free
IC646R-100UG
Carrier Free
IC646V-100UG
Carrier Free
IC646N-100UG
Carrier Free
IC646U-100UG
Carrier Free
IC646T-100UG
Carrier Free
IC646G-100
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IL-18/IL-1F4 Antibody (74801) [DyLight 405] Summary

Immunogen
E. coli-derived recombinant human IL‑18/IL‑1F4
Accession # Q14116
Specificity
Detects the pro region of human IL-18/IL-1F4 in direct ELISAs and Western blots. Does not cross‑react with recombinant human IL-18, recombinant mouse IL-18 or recombinant rat IL-18.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
IL18
Purity
Protein A or G purified from ascites
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry
  • Knockout Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from ascites

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-18/IL-1F4 Antibody (74801) [DyLight 405]

  • Iboctadekin
  • IFN-gamma-inducing factor
  • IGIF
  • IGIFIL-1 gamma
  • IL18
  • IL-18
  • IL-18MGC12320
  • IL-1F4
  • IL1F4iboctadekin
  • IL-1g
  • Interferon gamma-inducing factor
  • interleukin 18 (interferon-gamma-inducing factor)
  • Interleukin-1 gamma
  • interleukin-18

Background

The protein encoded by the IL18 gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL18