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IL-17B Antibody (174113) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, CyTOF-ready, ELISA, ELISA(Cap), ELISA(Det), Flow
Clone
174113
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

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IL-17B Antibody (174113) [DyLight 488] Summary

Immunogen
E. coli-derived recombinant human IL-17B
Gln21-Phe180
Accession # Q9UHF5
Specificity
Detects human IL-17B in Western blots and ELISAs. In Western blots, approximately 25% cross-reactivity with recombinant mouse IL‑17B is observed and no cross-reactivity with recombinant human (rh) IL‑17, rhIL-17C, rhIL-17E or rhIL-17F is observed. In sandwich immunoassays, less than 0.5% cross-reactivity with rmIL-17B, and no cross-reactivity with rhIL-17C, rhIL-17D, rhIL-17E, rhIL-17F, or rhIL-17 is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
IL17B
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA Capture (Matched Antibody Pair)
  • ELISA Detection (Matched Antibody Pair)
  • ELISA Standard (Matched Pair)
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-17B Antibody (174113) [DyLight 488]

  • Cytokine Zcyto7
  • cytokine-like protein ZCYTO7
  • IL17B
  • IL-17B
  • IL-17Binterleukin-17 beta
  • IL20
  • IL-20interleukin-17B
  • interleukin 17B
  • interleukin 20
  • Interleukin-20
  • MGC138900
  • MGC138901
  • neuronal interleukin-17 related factor
  • Neuronal interleukin-17-related factor
  • NIRF
  • ZCYTO7interleukin-20

Background

Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are IL-17B, IL-17C, and IL-17E. Like IL-17, IL-17B, C, and E are able to induce proinflammatory responses but don't bind to the IL-17 receptor suggesting additional IL-17R related receptors might exist. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in kidney and liver and at moderate level in small intestine, colon, and brain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol IL17B