Human IL-17F DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 10 of 13. Show All 13 Publications. Collapse Publications.

Publications using DY1335B	Applications	Species
CH Ho, AA Silva, B Tomita, HY Weng, IC Ho Differential impacts of TNFalpha inhibitors on the transcriptome of Th cells Arthritis Research & Therapy, 2021-07-23;23(1):199. 2021-07-23 [PMID: 34301319] (Human)		Human
J Luban, R Sattler, E Mühlberger, JD Graci, L Cao, M Weetall, C Trotta, JM Colacino, S Bavari, C Strambio-D, EL Suder, Y Wang, V Soloveva, K Cintron-Lu, NA Naryshkin, M Pykett, EM Welch, K O'Keefe, R Kong, E Goodwin, A Jacobson, S Paessler, S Peltz The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines Virus Res, 2020-11-26;0(0):198246. 2020-11-26 [PMID: 33249060] (Human)		Human
A Rajamanick, S Munisankar, CK Dolla, K Thiruvenga, S Babu Impact of malnutrition on systemic immune and metabolic profiles in type 2 diabetes BMC Endocr Disord, 2020-11-12;20(1):168. 2020-11-12 [PMID: 33183277] (Human)		Human
ML Tiirikaine, A Woetmann, H Norsgaard, LF Santamaria, P Lovato Ex vivo culture of lesional psoriasis skin for pharmacological testing J. Dermatol. Sci., 2019-12-27;0(0):. 2019-12-27 [PMID: 31948839] (Human)		Human
MS Wu, CH Wang, FC Tseng, HJ Yang, YC Lo, YP Kuo, DJ Tsai, WT Tsai, GY Yu Interleukin-17F expression is elevated in hepatitis C patients with fibrosis and hepatocellular carcinoma Infect. Agents Cancer, 2017-07-26;12(0):42. 2017-07-26 [PMID: 28770001] (Human)		Human
Mazerolles F, Picard C, Kracker S, Fischer A, Durandy A Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency. J Allergy Clin Immunol, 2013-02-10;131(4):1146-56, 1156. 2013-02-10 [PMID: 23403044] (Human)		Human
Yu RY, Gallagher G A naturally occurring, soluble antagonist of human IL-23 inhibits the development and in vitro function of human Th17 cells. J. Immunol., 2010-11-12;185(12):7302-8. 2010-11-12 [PMID: 21076058] (Human)		Human
Kisand K, Boe Wolff AS, Podkrajsek KT, Tserel L, Link M, Kisand KV, Ersvaer E, Perheentupa J, Erichsen MM, Bratanic N, Meloni A, Cetani F, Perniola R, Ergun-Longmire B, Maclaren N, Krohn KJ, Pura M, Schalke B, Strobel P, Leite MI, Battelino T, Husebye ES, Peterson P, Willcox N, Meager A Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines. J. Exp. Med., 2010-02-01;207(2):299-308. 2010-02-01 [PMID: 20123959] (Human)		Human
Xu G, Zhang L, Wang DY, Xu R, Liu Z, Han DM, Wang XD, Zuo KJ, Li HB Opposing roles of IL-17A and IL-25 in the regulation of TSLP production in human nasal epithelial cells. Allergy, 2009-11-25;65(5):581-9. 2009-11-25 [PMID: 19968632] (Human)		Human
Johansen C, Usher PA, Kjellerup RB Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin. Br. J. Dermatol., 2008-10-21;160(2):319-24. 2008-10-21 [PMID: 19016708] (Human)		Human
Watanabe H, Kawaguchi M, Fujishima S, Ogura M, Matsukura S, Takeuchi H, Ohba M, Sueki H, Kokubu F, Hizawa N, Adachi M, Huang SK, Iijima M Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis. J. Invest. Dermatol., 2008-10-02;129(3):650-6. 2008-10-02 [PMID: 18830271] (Human)		Human
Aujla SJ, Chan YR, Zheng M, Fei M, Askew DJ, Pociask DA, Reinhart TA, McAllister F, Edeal J, Gaus K, Husain S, Kreindler JL, Dubin PJ, Pilewski JM, Myerburg MM, Mason CA, Iwakura Y, Kolls JK IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat. Med., 2008-02-10;14(3):275-81. 2008-02-10 [PMID: 18264110] (Human)		Human
Schmechel S, Konrad A, Diegelmann J, Glas J, Wetzke M, Paschos E, Lohse P, Goke B, Brand S Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status. Inflamm. Bowel Dis., 2008-02-01;14(2):204-12. 2008-02-01 [PMID: 18022867] (Human)		Human
Show All 13 Publications. Collapse Publications.

Array DY1335B

• IL-17F Antibodies
• IL-17F ELISA Kit
• IL-17F Lysate
• IL-17F Protein
• IL-17F Proteins and Enzymes
• IL-17F ELISAs