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ICAM-4 Antibody

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Western Blot: ICAM-4 Antibody [NBP2-26177] - Staining of Human Umbillical Cord lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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ICAM-4 Antibody Summary

Immunogen
Peptide with sequence C-RHGSRVIYSESLER corresponding to internal region according to NP_001535.1, NP_071772.1.
Specificity
This antibody is expected to recognize isoform 1 (NP_001535.1) and isoform 2 (NP_071772.1) only.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
ICAM4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:64000
  • Western Blot 1 - 3 ug/ml
Application Notes
WB: Approx. 28 kDa band observed in human umbillical cord and in erythrocytes lysates (calculated MW of 29.3 kDa band according to NP_001535.1).
Publications
Read Publication using NBP2-26177.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ICAM-4 Antibody

  • CD242 antigen
  • CD242
  • ICAM4
  • ICAM-4
  • intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
  • intercellular adhesion molecule 4 (LW blood group)
  • intercellular adhesion molecule 4
  • intercellular adhesion molecule 4, Landsteiner-Wiener blood group
  • Landsteiner-Wiener blood group antigen a
  • Landsteiner-Wiener blood group glycoprotein
  • Landsteiner-Wiener blood group
  • LWLW blood group protein

Background

ICAM4 encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ICAM-4 Antibody (NBP2-26177)(1)

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for ICAM-4 Antibody (NBP2-26177) (0)

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Secondary Antibodies

 

Isotype Controls

Additional ICAM-4 Products

Blogs on ICAM-4.

Chromatin reader domains of DNMT-targeting protein, UHRF1, are responsible for cancerous DNA hypermethylation
By Jamshed Arslan, Pharm. D., PhD. DNA methylation represses transcription of many genes, including tumor suppressor genes. A protein called UHRF1 recruits DNA methyltransferases (DNMTs) to establish and maintain DNA...  Read full blog post.

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Bioinformatics

Gene Symbol ICAM4
Entrez