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Human VEGF-C DuoSet ELISA, 15 Plate

 (13 Publications)
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Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

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Human VEGF-C DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
VEGFC

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY752B.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human VEGF-C DuoSet ELISA, 15 Plate

  • Flt4 ligand
  • Flt4-L
  • vascular endothelial growth factor C
  • Vascular endothelial growth factor-related protein
  • VEGFC
  • VEGF-C
  • VRPFLT4 ligand DHM

Background

Vascular endothelial growth factor C (VEGF-C) is a homodimeric ligand of VEGF R3/Flt-4 and is synthesized with N- and C-terminal propeptides. Fully processed VEGF-C containing only the VEGF homology domain can additionally bind and activate VEGF R2/KDR/Flk-1. VEGF-C interactions with VEGF R3 are critical for lymphangiogenesis. Both the ligand and receptor are usually co-expressed at sites of lymphatic vessel sprouting, in the embryo, and in various pathological conditions. Over-expression of VEGF-C in tumor cells induces tumoral lymphatic hyperplasia, neoangiogenesis, and vessel sprouting, resulting in enhanced lymph flow and metastasis to regional lymph nodes.

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Publications for VEGF-C (DY752B)(13)

We have publications tested in 1 confirmed species: Human.


Filter By Application
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Filter By Species
Human
(13)
All Species
Showing Publications 1 - 10 of 13. Show All 13 Publications.
Publications using DY752B Applications Species
Shams, S;Stilhano, RS;Silva, EA; Harnessing EGLN1 Gene Editing to Amplify HIF-1 alpha and Enhance Human Angiogenic Response bioRxiv : the preprint server for biology 2023-05-30 [PMID: 37398294] (Human) Human
J Jiang, X Cong, S Alageel, U Dornseifer, AF Schilling, E Hadjipanay, HG Machens, P Moog In Vitro Comparison of Lymphangiogenic Potential of Hypoxia Preconditioned Serum (HPS) and Platelet-Rich Plasma (PRP) International Journal of Molecular Sciences, 2023-01-19;24(3):. 2023-01-19 [PMID: 36768283] (Human) Human
Y Ding, L Oliveira-F, E Vettorazzi, K Legler, K Milde-Lang, L Woelber, A Jaeger, K Prieske, V Mueller, B Schmalfeld, S Kuerti VEGF-C serum level is associated with response to bevacizumab maintenance therapy in primary ovarian cancer patients PLoS ONE, 2022-06-10;17(6):e0269680. 2022-06-10 [PMID: 35687576] (Human) Human
JP Lapuente, A Blázquez-M, J Marco-Brua, G Gómez, P Desportes, J Sanz, P Fernández, M García-Gil, F Bermejo, JV San Martín, A Algaba, JC De Gregori, D Lapuente, A De Gregori, B Lapuente, MV Andrés, A Anel Cytokine Profile and Anti-Inflammatory Activity of a Standardized Conditioned Medium Obtained by Coculture of Monocytes and Mesenchymal Stromal Cells (PRS CK STORM) Biomolecules, 2022-03-31;12(4):. 2022-03-31 [PMID: 35454123] (Human) Human
L Cristinzia, R Poto, G Criscuolo, AL Ferrara, MR Galdiero, L Modestino, S Loffredo, A de Paulis, G Marone, G Spadaro, G Varricchi IL-33 and Superantigenic Activation of Human Lung Mast Cells Induce the Release of Angiogenic and Lymphangiogenic Factors Cells, 2021-01-12;10(1):. 2021-01-12 [PMID: 33445787] (Human) Human
G Varricchi, S Loffredo, L Bencivenga, AL Ferrara, G Gambino, N Ferrara, A de Paulis, G Marone, G Rengo Angiopoietins, Vascular Endothelial Growth Factors and Secretory Phospholipase A2 in Ischemic and Non-Ischemic Heart Failure J Clin Med, 2020-06-19;9(6):. 2020-06-19 [PMID: 32575548] (Human) Human
G Varricchi, S Loffredo, F Borriello, A Pecoraro, F Rivellese, A Genovese, G Spadaro, G Marone Superantigenic Activation of Human Cardiac Mast Cells Int J Mol Sci, 2019-04-12;20(8):. 2019-04-12 [PMID: 31013832] (Human) Human
PD Ndiaye, M Dufies, S Giuliano, L Douguet, R Grépin, J Durivault, P Lenormand, N Glisse, J Mintcheva, V Vouret-Cra, B Mograbi, M Wurmser, D Ambrosetti, N Rioux-Lecl, P Maire, G Pagès VEGFC acts as a double-edged sword in renal cell carcinoma aggressiveness Theranostics, 2019-01-21;9(3):661-675. 2019-01-21 [PMID: 30809300] (Human) Human
J Bourland, J Fradette, FA Auger Tissue-engineered 3D melanoma model with blood and lymphatic capillaries for drug development Sci Rep, 2018-09-04;8(1):13191. 2018-09-04 [PMID: 30181613] (Human) Human
M Lupu-Plesu, A Claren, S Martial, PD N'Diaye, K Lebrigand, N Pons, D Ambrosetti, I Peyrottes, J Feuillade, J Hérault, M Dufies, J Doyen, G Pagès Effects of proton versus photon irradiation on (lymph)angiogenic, inflammatory, proliferative and anti-tumor immune responses in head and neck squamous cell carcinoma Oncogenesis, 2017-07-03;6(7):e354. 2017-07-03 [PMID: 28671677] (Human) Human
Show All 13 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for VEGF-C (DY752B). (Showing 1 - 1 of 1 FAQs).

  1. I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?
    • We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.

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Bioinformatics

Gene Symbol VEGFC