Human Serpin A1 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 10 of 18. Show All 18 Publications. Collapse Publications.

Publications using DY1268	Applications	Species
Cherpaz, M;Meugnier, E;Seillier, G;Pozzi, M;Pierrard, R;Leboube, S;Farhat, F;Vola, M;Obadia, JF;Amaz, C;Chalabreysse, L;May, C;Chanon, S;Brun, C;Givre, L;Bidaux, G;Mewton, N;Derumeaux, G;Bergerot, C;Paillard, M;Thibault, H; Myocardial transcriptomic analysis of diabetic patients with aortic stenosis: key role for mitochondrial calcium signaling Cardiovascular diabetology 2024-07-08 [PMID: 38978010] (Human)		Human
Park, KH;Lee, KN;Oh, E;Im, EM; Inflammatory biomarkers in the cervicovaginal fluid to identify histologic chorioamnionitis and funisitis in women with preterm labor Cytokine 2023-09-01 [PMID: 37536223] (Human)		Human
ZA Massy, O Lambert, M Metzger, M Sedki, A Chaubet, B Breuil, A Jaafar, I Tack, T Nguyen-Kho, M Alves, J Siwy, H Mischak, F Verbeke, G Glorieux, YE Herpe, JP Schanstra, B Stengel, J Klein, CKD-REIN s Machine Learning-Based Urine Peptidome Analysis to Predict and Understand Mechanisms of Progression to Kidney Failure Kidney international reports, 2022-12-12;8(3):544-555. 2022-12-12 [PMID: 36938091] (Human)		Human
B Kasztelan-, B Zygo, A Rycyk-Boja, A Surdacka, J Rolinski, H Cichoz-Lac Blood concentrations of mediators released from activated neutrophils are related to the severity of alcohol-induced liver damage PLoS ONE, 2023-01-06;18(1):e0280068. 2023-01-06 [PMID: 36607987] (Human)		Human
P Konstanti, M van Splunt, E van den Br, C Belzer, A Nauta, RJJ van Neerve, H Smidt The Effect of Nutritional Intervention with Lactoferrin, Galactooligosacharides and Vitamin D on the Gut Microbiota Composition of Healthy Elderly Women Nutrients, 2022-06-14;14(12):. 2022-06-14 [PMID: 35745198] (Human)		Human
DL Frey, C Bridson, S Dittrich, SY Graeber, M Stahl, S Wege, F Herth, O Sommerburg, C Schultz, A Dalpke, MA Mall, S Boutin Changes in Microbiome Dominance Are Associated With Declining Lung Function and Fluctuating Inflammation in People With Cystic Fibrosis Frontiers in Microbiology, 2022-05-13;13(0):885822. 2022-05-13 [PMID: 35633718] (Human)		Human
S Cambier, M Metzemaeke, AC Carvalho, A Nooyens, C Jacobs, L Vanderbeke, B Malengier-, M Gouwy, E Heylen, P Meersseman, G Hermans, E Wauters, A Wilmer, C Consortium, D Schols, P Matthys, G Opdenakker, RE Marques, J Wauters, J Vandooren, P Proost Atypical response to bacterial co-infection and persistent neutrophilic broncho-alveolar inflammation distinguish critical COVID-19 from influenza JCI Insight, 2022-01-11;0(0):. 2022-01-11 [PMID: 34793331] (Human)		Human
T Nakagiri, S Wrenger, K Sivaraman, F Ius, T Goecke, P Zardo, V Grau, T Welte, A Haverich, AK Knöfel, S Janciauski alpha1-Antitrypsin attenuates acute rejection of orthotopic murine lung allografts Respiratory Research, 2021-11-17;22(1):295. 2021-11-17 [PMID: 34789247] (Mouse)		Mouse
L Ostermann, R Maus, J Stolper, L Schütte, K Katsarou, S Tumpara, A Pich, C Mueller, S Janciauski, T Welte, UA Maus Alpha-1 antitrypsin deficiency impairs lung antibacterial immunity in mice JCI Insight, 2021-02-08;6(3):. 2021-02-08 [PMID: 33554955] (Mouse)		Mouse
M Golizeh, K Winter, L Roussel, M Landekic, M Langelier, VG Loo, M Ndao, DC Vinh Fecal host biomarkers predicting severity of Clostridioides difficile infection JCI Insight, 2021-01-11;0(0):. 2021-01-11 [PMID: 33232301] (Human)		Human
DM de Graaf, M Jaeger, ICL van den Mu, RT Horst, K Schraa, J Zwaag, M Kox, M Fujita, T Yamauchi, L Mercurio, S Madonna, JHW Rutten, J de Graaf, NP Riksen, FL van de Vee, MG Netea, LAB Joosten, CA Dinarello Reduced concentrations of the B cell cytokine Interleukin 38 are associated with cardiovascular disease risk in overweight subjects Eur J Immunol, 2020-11-19;0(0):. 2020-11-19 [PMID: 33125159] (Human)		Human
J Cassuto, A Folestad, J Göthlin, H Malchau, J Kärrholm Concerted actions by MMPs, ADAMTS and serine proteases during remodeling of the cartilage callus into bone during osseointegration of hip implants Bone Rep, 2020-09-11;13(0):100715. 2020-09-11 [PMID: 32995386] (Human)		Human
K Ogawa, T Kobayashi, JI Furukawa, H Hanamatsu, A Nakamura, K Suzuki, N Kawagishi, M Ohara, M Umemura, M Nakai, T Sho, G Suda, K Morikawa, M Baba, K Furuya, K Terashita, T Kobayashi, M Onodera, T Horimoto, K Shinada, S Tsunematsu, I Tsunematsu, T Meguro, T Mitsuhashi, M Hato, K Higashino, Y Shinohara, N Sakamoto Tri-antennary tri-sialylated mono-fucosylated glycan of alpha-1 antitrypsin as a non-invasive biomarker for non-alcoholic steatohepatitis: a novel glycobiomarker for non-alcoholic steatohepatitis Sci Rep, 2020-01-15;10(1):321. 2020-01-15 [PMID: 31941930] (Human)		Human
EP Reeves, DM Dunlea, K McQuillan, CA O'Dwyer, TP Carroll, R Saldova, PR Akepati, MR Wormald, OJ McElvaney, V Shutchaida, M Henry, P Meleady, J Keenan, DC Liberti, DN Kotton, PM Rudd, AA Wilson, NG McElvaney Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity J. Immunol., 2019-02-22;0(0):. 2019-02-22 [PMID: 30796179] (Human)		Human
T Kubo, M Tsujiwaki, Y Hirohashi, T Tsukahara, T Kanaseki, M Nakatsugaw, T Hasegawa, T Torigoe Differential bronchial epithelial response regulated by ?Np63: a functional understanding of the epithelial shedding found in asthma Lab. Invest., 2018-09-25;0(0):. 2018-09-25 [PMID: 30254318] (Human)		Human
Ramnik J Xavier Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity Cell, 2016-11-03;167(4):1125-1136.e8. 2016-11-03 [PMID: 27814509] (Human)		Human
Mihai G Netea Host and Environmental Factors Influencing Individual Human Cytokine Responses Cell, 2016-11-03;167(4):1111-1124.e13. 2016-11-03 [PMID: 27814508] (Human)		Human
Zager R, Johnson A, Frostad K Rapid renal alpha-1 antitrypsin gene induction in experimental and clinical acute kidney injury. PLoS ONE, 2014-05-21;9(5):e98380. 2014-05-21 [PMID: 24848503] (Human)		Human
Show All 18 Publications. Collapse Publications.

Array DY1268

• Serpin A1/alpha 1-Antitrypsin Antibodies
• Serpin A1/alpha 1-Antitrypsin Antibody Pair
• Serpin A1/alpha 1-Antitrypsin ELISA Kits
• Serpin A1/alpha 1-Antitrypsin Lysates
• Serpin A1/alpha 1-Antitrypsin Proteins
• Serpin A1/alpha 1-Antitrypsin Proteins and Enzyme
• Serpin A1/alpha 1-Antitrypsin ELISA