A lysate prepared from MDA-MB-468 human breast cancer cells treated with 50 mM sodium pervanadate for 20 minutes was analyzed with this ELISA. The Human Phospho-Src (Y419) Detection Antibody was either untreated (no ...read more
Quantification of phosphorylated Scr (Y419) in pervabadate-treated human MDA-MB-468 cells. Lysates prepared from MDA-MB-468 human breast cancer cells treated with 50 mM sodium pervanadate for the indicated times were ...read more
Src and other Src family protein tyrosine kinases are proto-oncogenes that play key roles in regulating cell growth and differentiation. Src family activity is regulated by tyrosine phosphorylation at two sites with opposing effects. Phosphorylation at Y419 of human Src up-regulates kinase activity, while phosphorylation at Y530 inactivates Src.
Androgen Receptor: What Makes a Man? Steroid receptors (SRs) are a superfamily of ligand-dependent nuclear transcription factors that activate responsive genes response to hormone. Androgen receptors (ARs) are found in a wide variety of tissues, including reproductive organs, central ner... Read full blog post.
The Heat is On: Heat Shock Proteins and the Link to Cancer Novus Biologicals offers an extensive antibody catalog targeting heat shock proteins (HSPs). A large protein group covering a number of families, the HSPs are functionally related by their dramatic upregulation in response to stress. Stress triggers m... Read full blog post.