Human Phospho-FGFR3 DuoSet IC ELISA, 2 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing

We have publications tested in 1 confirmed species: Human.

Showing Publication 1 - 1 of 1.

Publication using DYC2719-2	Applications	Species
Gavine PR, Mooney L, Kilgour E AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family. Cancer Res., 2012-02-27;72(8):2045-56. 2012-02-27 [PMID: 22369928] (Human)		Human

Array DYC2719-2

• FGFR3 Antibodies
• FGFR3 Antibody Pair
• FGFR3 Lysate
• FGFR3 ELISAs
• FGFR3 Proteins and Enzymes