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Human PDGF-BB Quantikine ELISA Kit

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human PDGF-BB Quantikine ELISA Kit Summary

Background
The Quantikine Human PDGF-BB Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human PDGF-BB in cell culture supernates, serum, or plasma. It contains E. coli-expressed recombinant human PDGF-BB and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human PDGF-BB showed linear curves that were parallel to the standard curves ...obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human PDGF-BB.
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Specificity
Natural and recombinant human PDGF-BB
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
PDGFB

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DBB00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human PDGF-BB Quantikine ELISA Kit

  • c-sis;IBGC5;PDGF2;PDGF-2;PDGFB;Platelet-derived growth factor subunit B;SIS;SSV
  • PDGFBB
  • PDGF-BB

Background

The platelet-derived growth factor (PDGF) family of disulfide-linked dimeric proteins consists of four homodimeric proteins, PDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD, and one heterodimeric protein, PDGF-AB. Members of this protein family act mainly on connective tissue. The dimeric isoforms of PDGF are expressed by different cell types and at different times during embryonic development. All PDGF isoforms are synthesized as inactive precursors and are processed to active forms that contain a PDGF/VEGF cysteine knot domain. Only PDGF-C and PDGF-D, also named spinal cord-derived growth factors SCDGF and SCDGF-B, also contain an N-terminal CUB domain. Mature PDGF dimers bind and induce the homo- or hetero-dimerization of two receptor tyrosine kinases (PDGF R alpha and R beta).

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for PDGF-BB (DBB00)(62)

We have publications tested in 7 confirmed species: Human, Mouse, Rat, Bovine, Equine, Porcine, Rabbit.


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Human
(51)
Mouse
(1)
Rat
(1)
Bovine
(1)
Equine
(3)
Porcine
(4)
Rabbit
(1)
All Species
Showing Publications 1 - 10 of 62. Show All 62 Publications.
Publications using DBB00 Applications Species
Iacovacci, J;Serafini, MS;Avuzzi, B;Badenchini, F;Cicchetti, A;Devecchi, A;Dispinzieri, M;Doldi, V;Giandini, T;Gioscio, E;Mancinelli, E;Noris Chiorda, B;Orlandi, E;Palorini, F;Possenti, L;Reis Ferreira, M;Villa, S;Zaffaroni, N;De Cecco, L;Valdagni, R;Rancati, T; Intestinal microbiota composition is predictive of radiotherapy-induced acute gastrointestinal toxicity in prostate cancer patients EBioMedicine 2024-07-18 [PMID: 39029427] (Human) Human
Scovino, AM;Dahab, EC;Diniz-Lima, I;de Senna Silveira, E;Barroso, SPC;Cardoso, KM;Nico, D;Makhoul, GJ;da Silva-Junior, EB;Freire-de-Lima, CG;Freire-de-Lima, L;Fonseca, LMD;Valente, N;Nacife, V;Machado, A;Araújo, M;Vieira, GF;Pauvolid-Corrêa, A;Siqueira, M;Morrot, A; A Comparative Analysis of Innate Immune Responses and the Structural Characterization of Spike from SARS-CoV-2 Gamma Variants and Subvariants Microorganisms 2024-04-02 [PMID: 38674664] (Human) Human
Ríos, S;González, LG;Saez, CG;Smith, PC;Escobar, LM;Martínez, CE; L-PRF Secretome from Both Smokers/Nonsmokers Stimulates Angiogenesis and Osteoblast Differentiation In Vitro Biomedicines 2024-04-16 [PMID: 38672228] (Human) Human
Mochizuki, T;Ushiki, T;Suzuki, K;Sato, M;Ishiguro, H;Suwabe, T;Watanabe, S;Edama, M;Omori, G;Yamamoto, N;Kawase, T; Elevated IL-1? and Comparable IL-1 Receptor Antagonist Levels Are Characteristic Features of L-PRP in Female College Athletes Compared to Male Professional Soccer Players International journal of molecular sciences 2023-12-14 [PMID: 38139317] (Human) Human
Mochizuki, T;Ushiki, T;Suzuki, K;Sato, M;Ishiguro, H;Suwabe, T;Edama, M;Omori, G;Yamamoto, N;Kawase, T; Characterization of Leukocyte- and Platelet-Rich Plasma Derived from Female Collage Athletes: A Cross-Sectional Cohort Study Focusing on Growth Factor, Inflammatory Cytokines, and Anti-Inflammatory Cytokine Levels International journal of molecular sciences 2023-09-02 [PMID: 37686398] (Human) Human
Schönborn, M;Gregorczyk-Maga, I;Batko, K;Maga, M;Bogucka, K;Gawlik, K;Pawlica-Gosiewska, D;Maga, P; Angiogenic and Microvascular Status Alterations after Endovascular Revascularization of Lower Limb Arteries among Patients with Diabetic Foot Syndrome: A Prospective 12-Month Follow-Up Study Journal of clinical medicine 2023-08-27 [PMID: 37685648] (Human) Human
Gregorczyk-Maga, I;Szustkiewicz-Karo?, A;Gajda, M;Kapusta, M;Maga, W;Schönborn, M; The Concentration of Pro- and Antiangiogenic Factors in Saliva and Gingival Crevicular Fluid Compared to Plasma in Patients with Peripheral Artery Disease and Type 2 Diabetes Biomedicines 2023-05-31 [PMID: 37371691] (Human) Human
Schönborn, M;Gregorczyk-Maga, I;Batko, K;Bogucka, K;Maga, M;P?otek, A;Pasieka, P;S?owi?ska-Solnica, K;Maga, P; Circulating Angiogenic Factors and Ischemic Diabetic Foot Syndrome Advancement-A Pilot Study Biomedicines 2023-05-27 [PMID: 37371653] (Human) Human
RO Ali, GM Quinn, R Umarova, JA Haddad, GY Zhang, EC Townsend, L Scheuing, KL Hill, M Gewirtz, S Rampertaap, SD Rosenzweig, AT Remaley, JM Han, V Periwal, H Cai, PJ Walter, C Koh, EB Levy, DE Kleiner, O Etzion, T Heller Longitudinal multi-omics analyses of the gut-liver axis reveals metabolic dysregulation in hepatitis C infection and cirrhosis Nature Microbiology, 2022-12-15;0(0):. 2022-12-15 [PMID: 36522461] (Human) Human
K Fukuda, T Kuroda, N Tamura, H Mita, H Miyata, Y Kasashima Platelet lysate enhances equine skeletal muscle regeneration in a bupivacaine-induced muscle injury model Journal of equine veterinary science, 2022-02-03;0(0):103892. 2022-02-03 [PMID: 35124154] (Equine) Equine
Show All 62 Publications.

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Bioinformatics

Gene Symbol PDGFB