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Human Lipocalin-2/NGAL Quantikine ELISA Kit

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Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human Lipocalin-2/NGAL Quantikine ELISA Kit Summary

Background
The Quantikine Human Lipocalin-2 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Lipocalin-2 in cell culture supernates, serum, plasma, urine, and saliva. It contains NS0-expressed recombinant human Lipocalin-2 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Lipocalin-2 showed linear curves that were parallel to t...he standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Lipocalin-2.
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Specificity
Natural and recombinant human Lipocalin-2
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
LCN2

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DLCN20.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Lipocalin-2/NGAL Quantikine ELISA Kit

  • 24p3
  • 25 kDa alpha-2-microglobulin-related subunit of MMP-9
  • HNL
  • LCN2
  • lipocalin 2 (oncogene 24p3)
  • lipocalin 2
  • Lipocalin2
  • Lipocalin-2
  • migration-stimulating factor inhibitor
  • MSFI
  • neutrophil gelatinase-associated lipocalin
  • NGAL
  • NGALlipocalin-2
  • Oncogene 24p3
  • p25
  • Siderocalin
  • Uterocalin

Background

The Lipocalin family comprises a diverse group of mostly secreted soluble proteins that bind hydrophobic ligands and act as transporters, carrying small molecules to specific cells. Lipocalins are related by possessing an 8-stranded beta-barrel structure. Lipocalin-1, also named tear lipocalin (TL), von Ebners gland protein (VEG) and tear pre-albumin, binds a large number of hydrophobic molecules and exhibits cysteine proteinase inhibitor and endonuclear activities. Lipocalin-2, also known as neutrophil gelatinase-associated lipocalin (NGAL), is a component of granules in neutrophils from tissues that are normally exposed to microorganisms and is upregulated during inflammation. Lipocalin-2 can form homodimers and can heterodimerize with the neutrophil gelatinase MMP-9.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Lipocalin-2/NGAL (DLCN20)(78)

We have publications tested in 2 confirmed species: Human, Rat.


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Human
(77)
Rat
(1)
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Showing Publications 1 - 10 of 78. Show All 78 Publications.
Publications using DLCN20 Applications Species
Wedasingha, S;Silva, A;Fakes, K;Siribaddana, S;Isbister, GK; Utility of Three Serum Biomarkers for Early Detection of Systemic Envenoming Following Viper Bites in Sri Lanka Annals of emergency medicine 2024-08-09 [PMID: 39127955] (Human) Human
Nawrocka-Millward, S;Biegus, J;Fudim, M;Guzik, M;Iwanek, G;Ponikowski, P;Zymli?ski, R; The role of urine chloride in acute heart failure Scientific reports 2024-06-18 [PMID: 38890417] (Human) Human
Tanahashi, H;Iwamoto, H;Yamaguchi, K;Sakamoto, S;Horimasu, Y;Masuda, T;Nakashima, T;Ohshimo, S;Fujitaka, K;Hamada, H;Hattori, N; Lipocalin-2 as a prognostic marker in patients with acute exacerbation of idiopathic pulmonary fibrosis Respiratory research 2024-05-04 [PMID: 38704585] (Human) Human
Kawakami, S;Yasuno, T;Kawakami, S;Ito, A;Fujimi, K;Matsuda, T;Nakashima, S;Masutani, K;Uehara, Y;Higaki, Y;Michishita, R; Effects of high-intensity intermittent exercise versus moderate-intensity continuous exercise on renal hemodynamics assessed by ultrasound echo Physiological reports 2024-01-01 [PMID: 38262710] (Human) Human
Musia?, K;Stojanowski, J;Mi?kiewicz-Bujna, J;Ka?wak, K;Ussowicz, M; KIM-1, IL-18, and NGAL, in the Machine Learning Prediction of Kidney Injury among Children Undergoing Hematopoietic Stem Cell Transplantation-A Pilot Study International journal of molecular sciences 2023-10-31 [PMID: 37958774] (Human) Human
Downes, KJ;Zuppa, AF;Sharova, A;Neely, MN; Optimizing Vancomycin Therapy in Critically Ill Children: A Population Pharmacokinetics Study to Inform Vancomycin Area under the Curve Estimation Using Novel Biomarkers Pharmaceutics 2023-04-25 [PMID: 37242578] (Human) Human
K Wolk, D Wilsmann-T, K Witte, TC Brembach, C Kromer, S Gerdes, K Ghoreschi, K Reich, R Mössner, R Sabat Interleukin-19 Levels Are Increased in Palmoplantar Pustulosis and Reduced following Apremilast Treatment International Journal of Molecular Sciences, 2023-01-09;24(2):. 2023-01-09 [PMID: 36674793] (Human) Human
FJ Manzano-Li, M Sanz-Gómez, D González-M, E Vega-Martí, M Gil-Ortega, A Schulz, MÁ Rubio, G Ruiz-Hurta, LM Ruilope, I Aránguez, R Kreutz, MS Fernández- Imbalance in Bone Morphogenic Proteins 2 and 7 Is Associated with Renal and Cardiovascular Damage in Chronic Kidney Disease International Journal of Molecular Sciences, 2022-12-20;24(1):. 2022-12-20 [PMID: 36613483] (Rat) Rat
SI Karampatso, G Paltoglou, SM Genitsarid, P Kassari, E Charmandar The Effect of a Comprehensive Life-Style Intervention Program of Diet and Exercise on Four Bone-Derived Proteins, FGF-23, Osteopontin, NGAL and Sclerostin, in Overweight or Obese Children and Adolescents Nutrients, 2022-09-13;14(18):. 2022-09-13 [PMID: 36145151] (Human) Human
TJ Kakkanattu, J Kaur, V Nagesh, M Kundu, K Kamboj, P Kaur, J Sethi, HS Kohli, KL Gupta, A Ghosh, V Kumar, AK Yadav, V Jha Serum myo-inositol oxygenase levels at hospital discharge predict progression to chronic kidney disease in community-acquired acute kidney injury Scientific Reports, 2022-08-02;12(1):13225. 2022-08-02 [PMID: 35918463] (Human) Human
Show All 78 Publications.

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Bioinformatics

Gene Symbol LCN2