Human CX3CL1/Fractalkine Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CX3CL1/Fractalkine is a transmembrane adhesion protein with a chemokine domain separated from the membrane by a mucin stalk. It is upregulated on many cell types during inflammation. The chemokine and mucin regions can be shed as a soluble chemokine that signals through the receptor CX3CR1. During extravasation, membrane-bound CX3CL1 traps leukocytes, then is cleaved to allow diapedesis. Soluble CX3CL1 protects neurons from microglial neurotoxicity, recruits macrophages for wound healing, recruits osteoclast precursors for bone resorption, and contributes to pathogenesis in coronary artery disease.

We have publications tested in 2 confirmed species: Human, Rat.

Showing Publications 1 - 10 of 25. Show All 25 Publications. Collapse Publications.

Publications using DCX310	Applications	Species
J Hesson, N Fudge, M Grant Cytomegalovirus Immunity, Inflammation and Cognitive Abilities in the Elderly Viruses, 2021-11-21;13(11):. 2021-11-21 [PMID: 34835127] (Human)		Human
S Ravichandr, G Grubbs, J Tang, Y Lee, C Huang, H Golding, S Khurana Systemic and mucosal immune profiling in asymptomatic and symptomatic SARS-CoV-2-infected individuals reveal unlinked immune signatures Science Advances, 2021-10-13;7(42):eabi6533. 2021-10-13 [PMID: 34644111] (Human)		Human
HR Jang, M Kim, S Hong, K Lee, MY Park, KE Yang, CJ Lee, J Jeon, KW Lee, JE Lee, JB Park, K Kim, GY Kwon, YG Kim, DJ Kim, W Huh Early postoperative urinary MCP-1 as a potential biomarker predicting acute rejection in living donor kidney transplantation: a prospective cohort study Scientific Reports, 2021-09-22;11(1):18832. 2021-09-22 [PMID: 34552150] (Human)		Human
S Sendic, L Mansouri, S Lundberg, A Nopp, SH Jacobson, J Lundahl B cell and monocyte phenotyping: A quick asset to investigate the immune status in patients with IgA nephropathy PLoS ONE, 2021-03-19;16(3):e0248056. 2021-03-19 [PMID: 33740017] (Human)		Human
A Helmke, AM Hüsing, S Gaedcke, N Brauns, MS Balzer, M Reinhardt, M Hiss, N Shushakova, D de Luca, I Prinz, H Haller, S von Vietin Peritoneal dialysate-range hypertonic glucose promotes T cell IL-17 production that induces mesothelial inflammation Eur. J. Immunol., 2020-09-30;0(0):. 2020-09-30 [PMID: 32926407] (Human)		Human
R Fu, H Guo, S Janga, M Choi, W Klinngam, MC Edman, SF Hamm-Alvar Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sj�gren's syndrome murine model Sci Rep, 2020-01-29;10(1):1455. 2020-01-29 [PMID: 31996771] (Human)		Human
A Mangold, TM Hofbauer, AS Ondracek, T Artner, T Scherz, WS Speidl, KA Krychtiuk, R Sadushi-Ko, J Jakowitsch, IM Lang Neutrophil extracellular traps and monocyte subsets at the culprit lesion site of myocardial infarction patients Sci Rep, 2019-11-08;9(1):16304. 2019-11-08 [PMID: 31704966] (Human)		Human
M Kashiwagi, T Imanishi, Y Ozaki, A Taruya, T Nishiguchi, Y Katayama, T Tanimoto, A Kuroi, T Kubo, A Tanaka, T Akasaka Prognostic Value of Human Peripheral Monocyte Subsets for Future Coronary Events in Patients Without Significant Coronary Artery Stenosis Circ. J., 2019-09-11;0(0):. 2019-09-11 [PMID: 31511449] (Human)		Human
EJ Im, CH Lee, PG Moon, GG Rangaswamy, B Lee, JM Lee, JC Lee, JG Jee, JS Bae, TK Kwon, KW Kang, MS Jeong, JE Lee, HS Jung, HJ Ro, S Jun, W Kang, SY Seo, YE Cho, BJ Song, MC Baek Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Nat Commun, 2019-03-27;10(1):1387. 2019-03-27 [PMID: 30918259] (Human)		Human
AM Hoffmann-V, SS Weigt, V Palchevski, E Volkmann, R Saggar, N Li, Ø Midtvedt, MB Lund, T Garen, MC Fishbein, A Ardehali, DJ Ross, T Ueland, P Aukrust, JP Lynch, RM Elashoff, Ø Molberg, JA Belperio Augmented concentrations of CX3CL1 are associated with interstitial lung disease in systemic sclerosis PLoS ONE, 2018-11-20;13(11):e0206545. 2018-11-20 [PMID: 30457999] (Human)		Human
X Huang, Y Zeng, Y Jiang, Y Qin, W Luo, S Xiang, SR Sooranna, L Pinhu Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-?B Mediators Inflamm., 2017-05-29;2017(0):9734837. 2017-05-29 [PMID: 28634422] (Rat)		Rat
M Kulkarni, E Bowman, J Gabriel, T Amburgy, E Mayne, DA Zidar, C Maierhofer, AN Turner, JA Bazan, SL Koletar, MM Lederman, SF Sieg, NT Funderburg Altered Monocyte and Endothelial Cell Adhesion Molecule Expression Is Linked to Vascular Inflammation in Human Immunodeficiency Virus Infection Open Forum Infect Dis, 2016-10-15;3(4):ofw224. 2016-10-15 [PMID: 28066794] (Human)		Human
Assessment of the Role of Metabolic Determinants on the Relationship between Insulin Sensitivity and Secretion PLoS ONE, 2016-12-21;11(12):e0168352. 2016-12-21 [PMID: 28002466] (Human)		Human
Boag S, Das R, Shmeleva E, Bagnall A, Egred M, Howard N, Bennaceur K, Zaman A, Keavney B, Spyridopoulos I T lymphocytes and fractalkine contribute to myocardial ischemia/reperfusion injury in patients. J Clin Invest, 2015-07-13;125(8):3063-76. 2015-07-13 [PMID: 26168217] (Human)		Human
Kassianos A, Wang X, Sampangi S, Afrin S, Wilkinson R, Healy H Fractalkine-CX3CR1-dependent recruitment and retention of human CD1c+ myeloid dendritic cells by in vitro-activated proximal tubular epithelial cells. Kidney Int, 2015-01-14;87(6):1153-63. 2015-01-14 [PMID: 25587706] (Human)		Human
Ostroff R, Mehan M, Stewart A, Ayers D, Brody E, Williams S, Levin S, Black B, Harbut M, Carbone M, Goparaju C, Pass H Early detection of malignant pleural mesothelioma in asbestos-exposed individuals with a noninvasive proteomics-based surveillance tool. PLoS ONE, 2012-10-03;7(10):e46091. 2012-10-03 [PMID: 23056237] (Human)		Human
Fractalkine is an independent predictor of mortality in patients with advanced heart failure. Thromb Haemost, 2012-09-26;108(6):1220-7. 2012-09-26 [PMID: 23014777] (Human)		Human
Stolla M, Pelisek J, von Bruhl M, Schafer A, Barocke V, Heider P, Lorenz M, Tirniceriu A, Steinhart A, Bauersachs J, Bray P, Massberg S, Schulz C Fractalkine is expressed in early and advanced atherosclerotic lesions and supports monocyte recruitment via CX3CR1. PLoS ONE, 2012-08-20;7(8):e43572. 2012-08-20 [PMID: 22916279] (Human)		Human
Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis. BMC Infect Dis, 2012-06-25;12(0):144. 2012-06-25 [PMID: 22731696] (Human)		Human
Activated innate immunity and the involvement of CX3CR1-fractalkine in promoting hematuria in patients with IgA nephropathy. Kidney Int., 2012-05-09;82(5):548-60. 2012-05-09 [PMID: 22572859] (Human)		Human
Xu Y, Zeng K, Han Y, Wang L, Chen D, Xi Z, Wang H, Wang X, Chen G Altered expression of CX3CL1 in patients with epilepsy and in a rat model. Am. J. Pathol., 2012-03-27;180(5):1950-62. 2012-03-27 [PMID: 22464888] (Human)		Human
Gaudin F, Nasreddine S, Donnadieu AC, Emilie D, Combadiere C, Prevot S, Machelon V, Balabanian K Identification of the chemokine CX3CL1 as a new regulator of malignant cell proliferation in epithelial ovarian cancer. PLoS ONE, 2011-07-07;6(7):e21546. 2011-07-07 [PMID: 21750716] (Human)		Human
Shah R, Hinkle CC, Ferguson JF, Mehta NN, Li M, Qu L, Lu Y, Putt ME, Ahima RS, Reilly MP Fractalkine is a novel human adipochemokine associated with type 2 diabetes. Diabetes, 2011-05-01;60(5):1512-8. 2011-05-01 [PMID: 21525510] (Human)		Human
Matsumiya T, Ota K, Imaizumi T Characterization of synergistic induction of CX3CL1/fractalkine by TNF-alpha and IFN-gamma in vascular endothelial cells: an essential role for TNF-alpha in post-transcriptional regulation of CX3CL1. J. Immunol., 2010-03-15;184(8):4205-14. 2010-03-15 [PMID: 20231691] (Human)		Human
Huang YW, Su P, Liu GY, Crow MR, Chaukos D, Yan H, Robinson LA Constitutive endocytosis of the chemokine CX3CL1 prevents its degradation by cell surface metalloproteases. J. Biol. Chem., 2009-09-01;284(43):29644-53. 2009-09-01 [PMID: 19723636] (Human)		Human
Show All 25 Publications. Collapse Publications.

Array DCX310

• CX3CL1/Fractalkine Antibodies
• CX3CL1/Fractalkine Antibody Pair
• CX3CL1/Fractalkine ELISA Kit
• CX3CL1/Fractalkine Proteins
• CX3CL1/Fractalkine Proteins and Enzymes
• CX3CL1/Fractalkine ELISAs