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Human Aggrecan DuoSet ELISA, 15 Plate

 (12 Publications)
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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

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Human Aggrecan DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
ACAN

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY1220.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Aggrecan DuoSet ELISA, 15 Plate

  • ACAN
  • AGC1
  • AGC1SEDK
  • aggrecan core protein
  • Aggrecan
  • Cartilage-specific proteoglycan core protein
  • Chondroitin sulfate proteoglycan 1
  • Chondroitin sulfate proteoglycan core protein 1
  • CSPCP
  • CSPG1
  • CSPG1aggrecan 1
  • CSPGCP
  • large aggregating proteoglycan
  • MSK16
  • MSK16AGCAN
  • SEDK

Background

Aggrecan belongs to the chondroitin sulfate (CS) proteoglycan family, which also includes Versican, Brevican, and Neurocan. Each Aggrecan molecule contains approximately 100 and 30 keratan sulfate and glycosaminoglycan (GAG) sidechains, respectively. Aggrecan non-covalently associates with hyaluronan via the link modules and an Ig domain in its N-terminus. It is the most abundant proteoglycan in cartilage, and contributes to the load-bearing capacity of this tissue.

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Human Aggrecan
DuoSet ELISA, 15 Plat
DY1220
Human Aggrecan DuoSet ELISA, 15 Plate
Species: Hu
Applications: ELISA

Publications for Aggrecan (DY1220)(12)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Rabbit.


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Human
(6)
Mouse
(4)
Rat
(1)
Rabbit
(1)
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Showing Publications 1 - 10 of 12. Show All 12 Publications.
Publications using DY1220 Applications Species
Snuggs, JW;Senter, RK;Whitt, JP;Jackson, JD;Le Maitre, CL; PCRX-201, a novel IL-1Ra gene therapy treatment approach for low back pain resulting from intervertebral disc degeneration Gene therapy 2024-11-21 [PMID: 39572769] (Human) Human
Sun, R;Zhu, J;Sun, K;Gao, L;Zheng, B;Shi, J; Strontium Ranelate Ameliorates Intervertebral Disc Degeneration via Regulating TGF-?1/NF-?B Axis International journal of medical sciences 2023-10-07 [PMID: 37928874] (Human) Human
L Jain, SM Bolam, AP Monk, JT Munro, E Chen, J Tamatea, N Dalbeth, RC Poulsen Differential Effects of Hypoxia versus Hyperoxia or Physoxia on Phenotype and Energy Metabolism in Human Chondrocytes from Osteoarthritic Compared to Macroscopically Normal Cartilage International Journal of Molecular Sciences, 2023-04-19;24(8):. 2023-04-19 [PMID: 37108698] (Human) Human
X Wang, D Wang, B Deng, L Yan Syringaresinol attenuates osteoarthritis via regulating the NF-kappaB pathway International immunopharmacology, 2023-03-28;118(0):109982. 2023-03-28 [PMID: 36989902] (Mouse) Mouse
Z Zhou, L Zhang, Y Liu, C Huang, W Xia, H Zhou, Z Zhou, X Zhou Luteolin Protects Chondrocytes from H2O2-Induced Oxidative Injury and Attenuates Osteoarthritis Progression by Activating AMPK-Nrf2 Signaling Oxidative Medicine and Cellular Longevity, 2022-02-01;2022(0):5635797. 2022-02-01 [PMID: 35154568] (Mouse) Mouse
J Cassuto, A Folestad, J Göthlin, H Malchau, J Kärrholm Concerted actions by MMPs, ADAMTS and serine proteases during remodeling of the cartilage callus into bone during osseointegration of hip implants Bone Rep, 2020-09-11;13(0):100715. 2020-09-11 [PMID: 32995386] (Human) Human
XH Xue, JX Xue, W Hu, FL Shi, Y Yang Nomilin targets the Keap1-Nrf2 signalling and ameliorates the development of osteoarthritis J. Cell. Mol. Med., 2020-06-21;0(0):. 2020-06-21 [PMID: 32564468] (Mouse) Mouse
D Chen, D Lu, H Liu, E Xue, Y Zhang, P Shang, X Pan Pharmacological blockade of PCAF ameliorates osteoarthritis development via dual inhibition of TNF-alpha-driven inflammation and ER stress EBioMedicine, 2019-11-14;0(0):. 2019-11-14 [PMID: 31735552] (Human) Human
Z Li, K Zhang, X Li, H Pan, S Li, F Chen, J Zhang, Z Zheng, J Wang, H Liu Wnt5a suppresses inflammation-driven intervertebral disc degeneration via a TNF-α/NF-κB -Wnt5a negative-feedback loop Osteoarthr. Cartil., 2018-04-12;0(0):. 2018-04-12 [PMID: 29656141] (Rat) Rat
F Wang, L Han, X Wang, Y Li, Y Zhu, J Wang, C Xue Sialoglycoprotein isolated from eggs of Carassius auratus promotes fracture healing in osteoporotic mice J Food Drug Anal, 2017-09-22;26(2):716-724. 2017-09-22 [PMID: 29567242] (Mouse) Mouse
Show All 12 Publications.

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Additional Aggrecan Products

Blogs on Aggrecan.

Check out the latest blog posts on Aggrecan.
Aches & Pains: Aggrecan in Joint Disease and Osteoarthritis
Aggrecan is essential for the normal function of articular cartilage and intervertebral discs. Aggrecan provides the ability for the tissues to withstand compressive loading. This property is dependent on both the high charge density endowed by its nu...  Read full blog post.
Read our latest blog and use the new citation tool on bio-techne.com

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Bioinformatics

Gene Symbol ACAN