Hormone-sensitive Lipase/HSL Antibody - BSA Free

Although initially described as an adipocyte-specific triacylglycerol lipase, lipe (also known as hormone-specific lipase or HSL) is expressed in multiple tissues and cell lines. It plays multiple roles in lipid metabolism, including hormone-stimulated lipolysis in adipose tissue and the hydrolysis of cholesterol esters. Lipe is expressed as a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesterol esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. Recently, it was observed that the lack of lipe in genetically obese leptin-null mice inhibited obesity and adipogenesis, suggesting that lipe plays a major role in adipocyte proliferation.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IHC-P.

Showing Publication 1 - 1 of 1.

Publication using NBP1-76735	Applications	Species
Xu M, Chang HH, Jung X et al. Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice BMC Cancer 2018-08-07 [PMID: 30086728] (IHC-P, Mouse)	IHC-P	Mouse

Array NBP1-76735

• Hormone-sensitive Lipase/HSL Antibodies
• Hormone-sensitive Lipase/HSL ELISA Kits
• Hormone-sensitive Lipase/HSL Lysate
• Hormone-sensitive Lipase/HSL Proteins