Orthogonal Strategies: Immunohistochemistry-Paraffin: HOOK1 Antibody [NBP1-81745] - Analysis in human testis and endometrium tissues using antibody. Corresponding HOOK1 RNA-seq data are presented for the same ...read more
Independent Antibodies: Immunohistochemistry-Paraffin: HOOK1 Antibody [NBP1-81745] - Staining of human colon, liver, lymph node and testis using Anti-HOOK1 antibody NBP1-81745 (A) shows similar protein ...read more
Western Blot: HOOK1 Antibody [NBP1-81745] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).
Western Blot: HOOK1 Antibody [NBP1-81745] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: ...read more
Immunohistochemistry-Paraffin: HOOK1 Antibody [NBP1-81745] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: HOOK1 Antibody [NBP1-81745] - Staining of human lymph node.
Immunohistochemistry-Paraffin: HOOK1 Antibody [NBP1-81745] - Staining of human liver.
Immunohistochemistry-Paraffin: HOOK1 Antibody [NBP1-81745] - Staining of human colon.
Immunohistochemistry-Paraffin: HOOK1 Antibody [NBP1-81745] - Staining of human endometrium shows no cytoplasmic positivity in glandular cells as expected.
This antibody was developed against Recombinant Protein corresponding to amino acids: KRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHC
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HOOK1
Purity
Immunogen affinity purified
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Mouse reactivity reported in scientific literature (26114544).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for HOOK1 Antibody
hHK1
HK1h-hook1
hook homolog 1 (Drosophila)
MGC10642
protein Hook homolog 1
Background
HOOK1 encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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