HMGA2 Antibody Summary
Description |
This product may not be purchased or sold within the European Union. Please contact customer service with any questions. |
Immunogen |
Peptide with sequence C-KAAQKKAEATGEK corresponding to internal region according to NP_003474.1, NP_003475.1. |
Specificity |
This antibody is expected to recognize both reported isoforms (NP_003474.1; NP_003475.1) and is not expected to cross-react with HMGA1. |
Predicted Species |
Canine (100%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
HMGA2 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Peptide ELISA Detection limit 1:8000
- Western Blot 1 - 3 ug/ml
|
Application Notes |
WB: Approx. 18 kDa band observed in human heart lysates is reported in scientific literature (PMID: 18505920). |
Publications |
|
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA |
Preservative |
0.02% Sodium Azide |
Concentration |
0.5 mg/ml |
Purity |
Immunogen affinity purified |
Notes
This product may not be purchased or sold within the European Union. Please contact customer service with any questions.
Alternate Names for HMGA2 Antibody
Background
This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for HMGA2 Antibody (NBP1-51985)(2)
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