HMGA2 Antibody (763)

HMGA2 encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Rat.

We have publications tested in 2 applications: IF/IHC, WB.

Showing Publications 1 - 2 of 2.

Publications using NBP2-43640	Applications	Species
Jiao W, Hao J, Xie y et al. EZH2 mitigates the cardioprotective effects of mesenchymal stem cell-secreted exosomes against infarction via HMGA2-mediated PI3K/AKT signaling BMC cardiovascular disorders 2022-03-09 [PMID: 35264108] (WB, Rat)	WB	Rat
Kondo Y, Hirabayashi K, Carreras J et al. The significance of tyrosine kinase receptor B and brain-derived neurotrophic factor expression in salivary duct carcinoma Biomed Mater 2020-11-26 [PMID: 33248386] (IF/IHC, Human)	IF/IHC	Human

Array NBP2-43640

• HMGA2 Antibodies
• HMGA2 ELISA Kits
• HMGA2 Lysates
• HMGA2 Proteins