Histone H1 Antibody (derlotuximab) [Alexa Fluor® 405]

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Histone H1 is the linker protein that is 194 amino acids long, weights approximately 21 kDa, and is part of a group of basic nuclear proteins called histones, which are responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Histone H1 has a shorter isoform measuring 177 amino acids long and weighing approximately 19 kDa as well. Current studies are being done on several diseases and disorders including paratyphoid fever, hemochromatosis, breast cancer, embryonal carcinoma, prostatitis, carcinoma, and neuronitis. This protein has also been shown to have interactions with ADPRH, CDK2, CDK7, CTCFL, and DOT1L in pathways such as the histone modification, DNA replication, chromosome condensation, PKA signaling, granzyme-A, and apoptosis pathways.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array NBP3-27977AF405

• Histone H1 Antibodies
• Histone H1 Protein