HIPK1 Antibody [Unconjugated] Summary
Immunogen |
E. coli-derived recombinant human HIPK1 Gln701-Ser900 Accession # Q86Z02 |
Specificity |
Detects endogenous human HIPK1 in Western blots. Approximately 15% cross reactivity to HIPK2 is observed in Western blot. |
Source |
N/A |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
HIPK1 |
Purity Statement |
Antigen Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative |
No Preservative |
Concentration |
LYOPH |
Reconstitution Instructions |
Reconstitute at 0.2 mg/mL in sterile PBS. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for HIPK1 Antibody [Unconjugated]
Background
HIPK1 (Homeodomain-interacting protein kinase 1) is a 120‑130 kDa member of the HIPK subfamily, CMGC Ser/Thr family of protein kinases. It is ubiquitously expressed, and plays a role in transcriptional regulation and signal transduction. Human HIPK1 is 1210 amino acids (aa) in length. It contains a protein kinase domain (aa 190‑518) that phosphorylates itself as well as Daxx and p53, an interaction region between aa 581‑847, a PEST sequence (aa 889‑973) and a YH domain (aa 1066‑1209) that recruits CtBP. Four different splice variants have been identified. Over aa 701‑900, human and mouse HIPK1 share 97% aa identity.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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