Hemoglobin beta Antibody (2H3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using H00003043-M01	Applications	Species
Li W, Xie S, Guo X et al. A novel transgenic mouse model produced from lentiviral germline integration for the study of beta-thalassemia gene therapy. Haematologica. 2008-03-01 [PMID: 18268280]
Xie SY, Ren ZR, Zhang JZ et al. Restoration of the balanced {alpha}/{beta}-globin gene expression in {beta}654-thalassemia mice using combined RNAi and antisense RNA approach. Hum Mol Genet. 2007-11-01 [PMID: 17716993]

Array H00003043-M01

• Hemoglobin beta Antibodies
• Hemoglobin beta ELISA Kits
• Hemoglobin beta Lysate
• Hemoglobin beta Proteins