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HAX-1 Antibody (3C5) - BSA Free

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Western Blot: HAX-1 Antibody (3C5) [NBP1-30169] - Cell lysates of HeLa (30ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human HAX1 (1:1000). Proteins were visualized using a goat ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clone
3C5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

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HAX-1 Antibody (3C5) - BSA Free Summary

Immunogen
Recombinant human HAX-1 (1-279aa) purified from E. coli
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
HAX1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:1000-1:2000

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4), 10% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for HAX-1 Antibody (3C5) - BSA Free

  • FLJ17042
  • FLJ93803
  • HAX1
  • HAX-1
  • HCLS1 (and PKD2) associated protein
  • HCLS1 associated protein X-1
  • HCLS1-associated protein X-1
  • HCLSBP1
  • HS1 binding protein
  • HS1-associating protein X-1
  • HS1-binding protein 1
  • HS1BP1
  • HS1BP1FLJ18492
  • HSP1BP-1
  • SCN3

Background

HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1 (HS1), one of the substrates of receptor-coupled tyrosine kinases activated during clonal expansion and deletion in lymphoid cells. It also interacts with the product of the polycystic kidney disease 2 (PKD2) gene and with the F-actin-binding protein, cortactin. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for HAX-1 Antibody (NBP1-30169) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HAX1
Entrez
Uniprot