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HAP1 Antibody

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Western Blot: HAP1 Antibody [NBP2-86664] - Host: Rabbit. Target Name: HAP1. Sample Tissue: Human U937 Whole Cell lysates. Antibody Dilution: 1ug/ml

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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HAP1 Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human HAP1. Peptide sequence: ETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYS The peptide sequence for this immunogen was taken from within the described region.
Clonality
Polyclonal
Host
Rabbit
Gene
HAP1
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for HAP1 Antibody

  • HAP2huntingtin-associated protein 2
  • hHLP1
  • HIP5
  • HLP1
  • HLPHAP-1
  • huntingtin-associated protein 1
  • Neuroan 1

Background

Huntington's disease is an autosomal dominant neurodegenerative disorder caused by an expanded polyglutamine repeat region in the huntingtin gene. Huntingtin-associated protein 1 (HAP1) is a huntingtin associated protein that shows neuronal localization and moves with huntingtin in nerve fibers. The ability of HAP1 to bind to huntingtin is enhanced by the expanded polyglutamine repeat region that is typical of the mutant form of the protein associated with Huntington's disease.

Defects with HAP1 can lead to Huntington's disease, and HAP1 antibodies are therefore useful tools for Huntington's disease research and neuroscience studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Array NBP2-86664

Research Areas for HAP1 Antibody (NBP2-86664)

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Bioinformatics

Gene Symbol HAP1