HAP1 Products

Description

Huntington's disease is an autosomal dominant neurodegenerative disorder caused by an expanded polyglutamine repeat region in the huntingtin gene. Huntingtin-associated protein 1 (HAP1) is a huntingtin associated protein that shows neuronal localization and moves with huntingtin in nerve fibers. The ability of HAP1 to bind to huntingtin is enhanced by the expanded polyglutamine repeat region that is typical of the mutant form of the protein associated with Huntington's disease.

Defects with HAP1 can lead to Huntington's disease, and HAP1 antibodies are therefore useful tools for Huntington's disease research and neuroscience studies.

Bioinformatics

Entrez	15114 Mouse 29430 Rat 9001 Human
Uniprot	AAI56729.1 Human CAC09418 Human HAP1_HUMAN Human NP_034534.1 Mouse P54256 Rat P54257 Human
Product By Gene ID	9001
Alternate Names	HAP2huntingtin-associated protein 2 hHLP1 HIP5 HLP1 HLPHAP-1 huntingtin-associated protein 1 Neuroan 1

Research Areas for HAP1

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Neuroscience