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GSDMDC1 Antibody (3G1A6) - Cleaved, N-terminal

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
3G1A6
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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GSDMDC1 Antibody (3G1A6) - Cleaved, N-terminal Summary

Immunogen
A synthetic peptide corresponding to residues surrounding Asp275 of human GSDMDC (NP_079012.3).

Sequence:
NFLTD
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
GSDMD
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA Recommended starting concentration is 1 ug/mL
  • Western Blot 1:500 - 1:1000
Theoretical MW
53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol, 0.05% BSA
Preservative
0.09% Sodium Azide
Purity
Affinity purified

Alternate Names for GSDMDC1 Antibody (3G1A6) - Cleaved, N-terminal

  • DF5L
  • DFNA5L
  • FKSG10
  • FLJ12150
  • gasdermin D
  • gasdermin domain containing 1
  • Gasdermin domain-containing protein 1
  • gasdermin-D
  • GSDMD N
  • GSDMD
  • GSDMDC1
  • GSDMD-N
  • hGSDMD-CTD)

Background

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation ofepithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively splicedtranscript variants have been described. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Pyroptosis: Mechanisms mediating cell death and pro-inflammatory cytokine release
By Victoria OsinskiPyroptosis is an inflammatory form of programmed cell death characterized by the release of pro-inflammatory cytokines IL-1 beta and IL-18.1,10 It is a process distinct from apoptosis and necrosis (T...  Read full blog post.

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Bioinformatics

Gene Symbol GSDMD