Gr-1/Ly-6G Antibody (RB6-8C5) [Phycoerythrin]

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Mouse splenocytes were stained with Rat Anti-Mouse B220/CD45R APC-conjugated Monoclonal Antibody (Catalog # FAB1217A) and either (A) Rat Anti-Mouse Gr-1/Ly-6G PE-conjugated Monoclonal Antibody (Catalog # FAB1037P) or ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
RB6-8C5
Clonality
Monoclonal
Host
Rat
Conjugate
Phycoerythrin

Order Details

Gr-1/Ly-6G Antibody (RB6-8C5) [Phycoerythrin] Summary

Immunogen
The immunogen for this antibody is Ly-6G (Gr-1, Gr1).
Specificity
Detects mouse Gr-1/Ly-6G. Weak cross-reactivity with Ly-6C is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
Ly6g
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB1037P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Gr-1/Ly-6G Antibody (RB6-8C5) [Phycoerythrin]

  • Gr1
  • Gr-1
  • Ly-6C
  • Ly6G
  • Ly-6G
  • ly-6G.1
  • Ly-6G/Ly-6C (Gr-1)
  • lymphocyte antigen 6 complex, locus G
  • lymphocyte antigen 6G

Background

The myeloid differentiation antigen Gr-1 is a member of the Ly-6 family, Ly-6G (1). The RB6‑8C5 antibody also reacts weakly with Ly-6C-transfected EL4 cells (2). In the periphery, this antibody specifically recognized granulocytes (3, 4).
  1. Spangrude, G.J. et al. (1988) Science 241:58.
  2. Fleming, T.J. et al. (1993) J. Immunol. 151:2399.
  3. Lewinsohn, D.M. et al.(1987) J. Immunol. 147:22.
  4. Lagasse, E. and I.L. Weissman (1996) J. Immunol. Methods 197:139.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Gr-1/Ly-6G Antibody (FAB1037P)(6)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: Flow Cytometry, Functional Assay.


Filter By Application
Flow Cytometry
(5)
Functional Assay
(1)
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Filter By Species
Mouse
(6)
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Showing Publications 1 - 6 of 6.
Publications using FAB1037P Applications Species
K Shimura, S Mabuchi, N Komura, E Yokoi, K Kozasa, T Sasano, M Kawano, Y Matsumoto, T Watabe, M Kodama, K Hashimoto, K Sawada, J Hatazawa, T Kimura Prognostic significance of bone marrow FDG uptake in patients with gynecological cancer Scientific Reports, 2021-01-26;11(1):2257. 2021-01-26 [PMID: 33500424] (Flow Cytometry, Mouse) Flow Cytometry Mouse
K Kozasa, S Mabuchi, Y Matsumoto, H Kuroda, E Yokoi, N Komura, M Kawano, R Takahashi, T Sasano, K Shimura, M Kodama, K Hashimoto, K Sawada, K Nagasaka, T Kimura Estrogen stimulates female cancer progression by inducing myeloid-derived suppressive cells: investigations on pregnant and non-pregnant experimental models Oncotarget, 2019-03-08;10(20):1887-1902. 2019-03-08 [PMID: 30956772] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Heim C, Vidlak D, Scherr T, Hartman C, Garvin K, Kielian T IL-12 promotes myeloid-derived suppressor cell recruitment and bacterial persistence during Staphylococcus aureus orthopedic implant infection. J Immunol, 2015-03-11;194(8):3861-72. 2015-03-11 [PMID: 25762781] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Forget M, Voorhees J, Cole S, Dakhlallah D, Patterson I, Gross A, Moldovan L, Mo X, Evans R, Marsh C, Eubank T Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer. PLoS ONE, 2014-06-03;9(6):e98623. 2014-06-03 [PMID: 24892425] (Functional Assay, Mouse) Functional Assay Mouse
Ramadas R, Ewart S, Iwakura Y, Medoff B, Levine A IL-36alpha exerts pro-inflammatory effects in the lungs of mice. PLoS ONE, 2012-09-20;7(0):e45784. 2012-09-20 [PMID: 23029241] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Salvucci O, Jiang K, Gasperini P MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular cell adhesion molecule 1. Haematologica, 2012-01-22;97(6):818-26. 2012-01-22 [PMID: 22271895] (Flow Cytometry, Mouse) Flow Cytometry Mouse

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Bioinformatics

Gene Symbol Ly6g