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GluR2 Antibody (3A11) [Janelia Fluor® 635]

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Product Details

Summary
Reactivity Hu, Rt, PmSpecies Glossary
Applications WB, ELISA, Func, ICC/IF, IHC, IP
Clone
3A11
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 635

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GluR2 Antibody (3A11) [Janelia Fluor® 635] Summary

Immunogen
Recombinant fusion protein TrpE-GluR2.
Specificity
Glutamate Receptor 2 (GluR2) by Western Blot and RIA. When using MAB396 for immunohistochemistry or immunoprecipitation it recognizes both GluR2 and GluR4.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GRIA2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
  • Radioimmunoassay
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for GluR2 Antibody (3A11) [Janelia Fluor® 635]

  • AMPA 2
  • AMPA2
  • GluA2
  • GluR2
  • GLURB
  • GluR-K2
  • glutamate receptor, ionotropic, AMPA 2
  • GRIA2
  • HBGR2

Background

The GRIA2 gene encodes for glutamate receptor 2 with an isoform flop of 883 amino acids, 98 kDA, isoform flip of 883 amino acids and 98 kDA, and an isoform 3 of 901 amino acids long and 100 kDA. Glutamate receptors function as a ligand-gated ion channel in the central nervous system and are the predominant excitatory neurotransmitter receptors in the brain. GRIA2 has been researched regarding its role in Alzheimer's disease, multiple sclerosis, motor neuron disease, epilepsy, anorexia, bioplar disorder, and neurodegeneration. GRIA2 is involved in the CREB pathway, intracellular calcium signaling, glutamic acid signaling, and calcium channels as well as interacts with genes NSF, GRIA3, DLG4, GRID2, and SDCBP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol GRIA2