GKAP/DLGAP1 Antibody - BSA Free

SAP90/PSD-95-associated protein 1 (SAPAP1, also known as DLGAP1 or GKAP) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP1 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP1 mRNA is targeted to cell bodies in a similar manner to SAPAP2 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse and is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM). At least three isoforms of SAPAP1 are known to exist. This SAPAP1 antibody will not cross-react with other SAPAP proteins.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Rat.

Showing Publications 1 - 2 of 2.

Publications using NBP1-76911	Applications	Species
Hacisuleyman E, Hale CR, Noble N et Al. Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding Nat Neurosci 2024-04-08 [PMID: 38589584]
Richter Katharina N, Wildhagen Hanna, Helm Martin S et al. Comparative synaptosome imaging: a semi-quantitative method to obtain copy numbers for synaptic and neuronal proteins. Scientific Reports 2018-10-04 [PMID: 30287847] (Rat)		Rat

Array NBP1-76911

• GKAP/DLGAP1 Antibodies
• GKAP/DLGAP1 Protein