Home » GFR alpha-2/GDNF R alpha-2 » GFR alpha-2/GDNF R alpha-2 Antibodies » GFR alpha-2/GDNF R alpha-2 Antibody (101) [DyLight 755]
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GFR alpha-2/GDNF R alpha-2 Antibody (101) [DyLight 755]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Clone
101
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 755

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-89419AF350
Alexa Fluor 405
NBP2-89419AF405
Alexa Fluor 488
NBP2-89419AF488
Alexa Fluor 532
NBP2-89419AF532
Alexa Fluor 594
NBP2-89419AF594
Alexa Fluor 647
NBP2-89419AF647
Alexa Fluor 700
NBP2-89419AF700
Alexa Fluor 750
NBP2-89419AF750
Allophycocyanin
NBP2-89419APC
Biotin
NBP2-89419B
CoraFluor 1
NBP2-89419CL1
DyLight 350
NBP2-89419UV
DyLight 405
NBP2-89419V
DyLight 488
NBP2-89419G
DyLight 550
NBP2-89419R
DyLight 594
NBP2-89419DL594
DyLight 650
NBP2-89419C
DyLight 680
NBP2-89419FR
FITC
NBP2-89419F
HRP
NBP2-89419H
Janelia Fluor 525
NBP2-89419JF525
Janelia Fluor 549
NBP2-89419JF549
Janelia Fluor 646
NBP2-89419JF646
Janelia Fluor 669
NBP2-89419JF669
PE
NBP2-89419PE
PerCP
NBP2-89419PCP
Unconjugated
NBP2-89419-100ul
mFluor Violet 450 SE
NBP2-89419MFV450
mFluor Violet 500 SE
NBP2-89419MFV500
mFluor Violet 610 SE
NBP2-89419MFV610
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GFR alpha-2/GDNF R alpha-2 Antibody (101) [DyLight 755] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Human GFR alpha-2/GDNF R alpha-2 (Accession#: NP_001486.4; Met 1-Ser 441).
Specificity
No cross-reactivity in ELISA with:

Human GFRa3
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
GFRA2
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for GFR alpha-2/GDNF R alpha-2 Antibody (101) [DyLight 755]

  • GDNF family receptor alpha 2
  • GDNF family receptor alpha-2
  • GDNF R alpha-2
  • GDNF receptor alpha-2
  • GDNF receptor beta
  • GDNFR-alpha-2
  • GDNFR-beta
  • GDNFRBRET ligand 2
  • GFR alpha2
  • GFR alpha-2
  • GFRA2
  • GFRa-2
  • GFR-alpha 2
  • GFR-alpha-2
  • glial cell line derived neurotrophic factor receptor, beta
  • Neurturin receptor alpha
  • NRTNR-alpha
  • NTNRA
  • NTNR-alpha
  • PI-linked cell-surface accessory protein
  • RETL2TGF-beta-related neurotrophic factor receptor 2
  • TGF-beta related neurotrophic factor receptor 2
  • TRN receptor, GPI-anchored
  • TRNR2NRTNR-ALPHA

Background

Members of the glial cell line derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN), play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRa, which is a cell surface receptor for NTN. The cDNAs encoding NTNRa from human, rat, chicken, and mouse have been cloned recently. NTNRa was also termed GDNFRb, Ret ligand 2 (RETL2) or TGFb related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRa2 recently. GFRa2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GFRA2