GFR alpha-1/GDNF R alpha-1 Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Glial cell line-derived growth factor (GDNF), neurturin (NTN) and persephin, distant members of the TGF-beta  superfamily, are neurotrophic factors for a variety of neuronal populations in the central and peripheral nervous systems. The bioactivities of GDNF and NTN are mediated through a receptor complex composed of the non ligand-binding signaling subunit (c-Ret receptor tyrosine kinase) and either of two ligand binding subunits (GDNF receptor alpha - (GFR alpha -1) or GFR alpha -2). GFR alpha -1 and
‑2 are members of a family of at least four cysteine-rich glycosyl-phosphatidylinositol (GPI)-linked cell surface proteins that share conserved placements of many of their cysteine residues. Binding of GDNF to membrane-associated GFR alpha -1 or GFR alpha -2 initiates the association with and activation of the Ret tyrosine kinase. Soluble GFR alpha s released enzymatically from the cell surface-associated protein with phosphatidylinositol phospholipase C, as well as recombinantly produced soluble GFR alpha -1, can also bind with high-affinity to GDNF and trigger the activation of Ret tyrosine kinase. Rat GFR alpha -1 cDNA encodes a 468 amino acid (aa) residue protein with an
N‑terminal 24 aa residue hydrophobic signal peptide. Like other GPI-linked proteins, rat GFR alpha -1 has a C-terminal hydrophobic region which is preceded by a three aa residue (ASS) GPI-binding site. Human GFR alpha -1 shares 93% amino acid identity with rat GFR alpha -1. The expression of the various GFR alpha s are differentially regulated in the central and peripheral nervous system, suggesting complementary roles for the GFR alpha s in mediating the activities of the GDNF family of neurotrophic factors.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 6 confirmed species: Human, Mouse, Rat, Chicken, Porcine, Transgenic Mouse.

We have publications tested in 9 applications: Flow Cytometry, ICC, IHC, IHC-Fr, IHC-P, Immunochromatography, Immunohistochemistry, Neutralization, Western Blot.

Showing Publications 1 - 10 of 71. Show All 71 Publications. Collapse Publications.

Publications using AF560	Applications	Species
Yang, SH;Zeng, YZ;Jia, XZ;Gu, YW;Wood, C;Yang, RS;Yang, JS;Yang, WJ; Activated dormant stem cells recover spermatogenesis in chemoradiotherapy-induced infertility Cell reports 2024-08-02 [PMID: 39096488] (Immunohistochemistry, Mouse)	Immunohistochemistry	Mouse
Nitahara, K;Kawamura, A;Kitamura, Y;Kato, K;Namekawa, SH;Nishiyama, M; Chromatin remodeler CHD8 is required for spermatogonial proliferation and early meiotic progression Nucleic acids research 2024-01-16 [PMID: 38224953] (IHC, Transgenic Mouse)	IHC	Transgenic Mouse
Anbarci, DN;McKey, J;Levic, DS;Bagnat, M;Capel, B; Rediscovering the Rete Ovarii: a secreting auxiliary structure to the ovary bioRxiv : the preprint server for biology 2023-11-11 [PMID: 37986754] (IHC, Mouse)	IHC	Mouse
Penny A. F. Whiley, Benedict Nathaniel, Peter G. Stanton, Robin M. Hobbs, Kate L. Loveland Spermatogonial fate in mice with increased activin A bioactivity and testicular somatic cell tumours Frontiers in Cell and Developmental Biology 7/26/2023 [PMID: 37564373]
X Feng, T Matsumura, Y Yamashita, T Sato, K Hashimoto, H Odaka, Y Makino, Y Okada, H Nakamura, H Kimura, T Fujii, T Ogawa In vitro spermatogenesis in isolated seminiferous tubules of immature mice PLoS ONE, 2023;18(4):e0283773. 2023 [PMID: 37023052] (IHC, Mouse)	IHC	Mouse
X Feng, T Matsumura, Y Yamashita, T Sato, K Hashimoto, H Odaka, Y Makino, Y Okada, H Nakamura, H Kimura, T Fujii, T Ogawa In vitro spermatogenesis in isolated seminiferous tubules of immature mice PLoS ONE, 2023-04-06;18(4):e0283773. 2023-04-06 [PMID: 37023052] (IHC, Mouse)	IHC	Mouse
Yi Jacky Peng, Xinyu Thomas Tang, Hui Sophie Shu, Wenjie Dong, Hongfang Shao, Bo O. Zhou Sertoli cells are the unique source of stem cell factor for spermatogenesis Development 3/15/2023 [PMID: 36861441]
A Uchida, K Imaimatsu, H Suzuki, X Han, H Ushioda, M Uemura, K Imura-Kish, R Hiramatsu, HM Takase, Y Hirate, A Ogura, M Kanai-Azum, A Kudo, Y Kanai SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse Nature Communications, 2022-12-21;13(1):7860. 2022-12-21 [PMID: 36543770] (IHC, Mouse)	IHC	Mouse
MN Khan, P Cherukuri, F Negro, A Rajput, P Fabrowski, V Bansal, C Lancelin, TI Lee, Y Bian, WP Mayer, T Akay, D Müller, S Bonn, D Farina, T Marquardt ERR2 and ERR3 promote the development of gamma motor neuron functional properties required for proprioceptive movement control PloS Biology, 2022-12-21;20(12):e3001923. 2022-12-21 [PMID: 36542664] (IHC, Human)	IHC	Human
Manuela Nieto-Rostro, Ryan Patel, Anthony H. Dickenson, Annette C. Dolphin Nerve injury increases native Ca V 2.2 trafficking in dorsal root ganglion mechanoreceptors Pain 6/1/2023 [PMID: 36524581]
Quinton Blount, Ignacio Hernandez‐Morato, Yalda Moayedi, Michael J. Pitman Expression of Glial Cell‐Derived Neurotrophic Factor Receptors Within Nucleus Ambiguus During Rat Development The Laryngoscope 9/1/2023 [PMID: 36271908]
Oleksandr Kirsanov, Taylor Johnson, Taylor Malachowski, Bryan A. Niedenberger, Emma A. Gilbert, Debajit Bhowmick et al. Modeling mammalian spermatogonial differentiation and meiotic initiation in vitro Development 11/15/2022 [PMID: 36250451]
Ram Prakash Yadav, Sini Leskinen, Lin Ma, Juho-Antti Mäkelä, Noora Kotaja Chromatin remodelers HELLS, WDHD1 and BAZ1A are dynamically expressed during mouse spermatogenesis Reproduction 1/1/2023 [PMID: 36194437]
Hirano K, Nonami Y, Nakamura Y et al. Temperature sensitivity of DNA double-strand break repair underpins heat-induced meiotic failure in mouse spermatogenesis Communications Biology 2022-05-26 [PMID: 35618762]
Hirano K, Nonami Y, Nakamura Y et al. Temperature sensitivity of DNA double-strand break repair underpins heat-induced meiotic failure in mouse spermatogenesis Communications Biology 5/26/2022 [PMID: 35618762]
V Barroca, C Racine, L Pays, P Fouchet, M Coureuil, I Allemand The netrin-1 receptor UNC5C contributes to the homeostasis of undifferentiated spermatogonia in adult mice Stem Cell Research, 2022-02-25;60(0):102723. 2022-02-25 [PMID: 35247845] (IHC, Mouse)	IHC	Mouse
Qianxing Z, Lele Y, Ruona S et al. Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis. iScience. 2021-10-30 [PMID: 34825148]
Qianxing Z, Lele Y, Ruona S et al. Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis. iScience. 10/30/2021 [PMID: 34825148]
Vladimir Vladimirovich Muzyka, Tudor Constantin Badea Genetic interplay between transcription factor Pou4f1/Brn3a and neurotrophin receptor Ret in retinal ganglion cell type specification Neural Development 12/1/2021 [PMID: 34548095]
Y Mori, S Takashima, M Kanatsu-Sh, Z Yi, T Shinohara Cdc42 is required for male germline niche development in mice Cell Reports, 2021-08-17;36(7):109550. 2021-08-17 [PMID: 34407418] (ICC, Mouse)	ICC	Mouse
T Yamamuro, S Nakamura, Y Yamano, T Endo, K Yanagawa, A Tokumura, T Matsumura, K Kobayashi, H Mori, Y Enokidani, G Yoshida, H Imoto, T Kawabata, M Hamasaki, A Kuma, S Kuribayash, K Takezawa, Y Okada, M Ozawa, S Fukuhara, T Shinohara, M Ikawa, T Yoshimori Rubicon prevents autophagic degradation of GATA4 to promote Sertoli cell function PloS Genetics, 2021-08-05;17(8):e1009688. 2021-08-05 [PMID: 34351902] (IHC, Mouse)	IHC	Mouse
Osawa Y, Murata K, Usui M et al. EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice eLife 5/11/2021 [PMID: 33973520]
Shinnosuke Suzuki, John R. McCarrey, Brian P. Hermann Differential RA responsiveness among subsets of mouse late progenitor spermatogonia Reproduction 6/1/2021 [PMID: 33835049]
K Imura-Kish, A Uchida, N Tsunekawa, H Suzuki, HM Takase, Y Hirate, M Kanai-Azum, R Hiramatsu, M Kurohmaru, Y Kanai Low retinoic acid levels mediate regionalization of the Sertoli valve in the terminal segment of mouse seminiferous tubules Scientific Reports, 2021-01-13;11(1):1110. 2021-01-13 [PMID: 33441739] (IHC, Mouse)	IHC	Mouse
A Tsuchimoto, M Tone, N Ogonuki, M Hada, A Ogura, S Takashima Germ cell depletion in recipient testis has adverse effects on spermatogenesis in orthotopically transplanted testis pieces via retinoic acid insufficiency Sci Rep, 2020-07-01;10(1):10796. 2020-07-01 [PMID: 32612133] (IHC, Mouse)	IHC	Mouse
A Bonafina, MF Trinchero, AS Ríos, P Bekinschte, AF Schinder, G Paratcha, F Ledda GDNF and GFRalpha1 Are Required for Proper Integration of Adult-Born Hippocampal Neurons Cell Rep, 2019-12-24;29(13):4308-4319.e4. 2019-12-24 [PMID: 31875542] (IHC, Mouse)	IHC	Mouse
Grigor Varuzhanyan, Rebecca Rojansky, Michael J Sweredoski, Robert L J Graham, Sonja Hess, Mark S Ladinsky et al. Mitochondrial fusion is required for spermatogonial differentiation and meiosis eLife 10/9/2019 [PMID: 31596236]
Manju Sharma, Anuj Srivastava, Heather E Fairfield, David Bergstrom, William F Flynn, Robert E Braun Identification of EOMES-expressing spermatogonial stem cells and their regulation by PLZF eLife 5/31/2019 [PMID: 31149899]
Yi-Ping Cao, Yu-Chuan Zhou, Ming-Han Tong, Yong-Lian Zhang, Ming-Han Tong, Yong-Lian Zhang Mechanistic target of rapamycin kinase (Mtor) is required for spermatogonial proliferation and differentiation in mice Asian Journal of Andrology 1/1/2020 [PMID: 31134915]
JMD Legrand, AL Chan, HM La, FJ Rossello, ML Änkö, FV Fuller-Pac, RM Hobbs DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia Nat Commun, 2019;10(1):2278. 2019 [PMID: 31123254] (IHC, Rat)	IHC	Rat
RL Tang, LQ Fan PLZFposc-KITpos-delineated A1-A4-differentiating spermatogonia by subset and stage detection upon Bouin fixation Asian J. Androl., 2019-05-01;21(3):309-318. 2019-05-01 [PMID: 30719983] (IHC, Mouse)	IHC	Mouse
BP Hermann, K Cheng, A Singh, L Roa-De La, KN Mutoji, IC Chen, H Gilderslee, JD Lehle, M Mayo, B Westernstr, NC Law, MJ Oatley, EK Velte, BA Niedenberg, D Fritze, S Silber, CB Geyer, JM Oatley, JR McCarrey The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids Cell Rep, 2018-11-06;25(6):1650-1667.e8. 2018-11-06 [PMID: 30404016] (IHC-Fr, Mouse)	IHC-Fr	Mouse
J Guo, EJ Grow, H Mlcochova, GJ Maher, C Lindskog, X Nie, Y Guo, Y Takei, J Yun, L Cai, R Kim, DT Carrell, A Goriely, JM Hotaling, BR Cairns The adult human testis transcriptional cell atlas Cell Res., 2018-10-12;0(0):. 2018-10-12 [PMID: 30315278] (IHC-P, Human)	IHC-P	Human
Nicholas Serra, Ellen K Velte, Bryan A Niedenberger, Oleksander Kirsanov, Christopher B Geyer The mTORC1 component RPTOR is required for maintenance of the foundational spermatogonial stem cell pool in mice† Biology of Reproduction 2/1/2019 [PMID: 30202948]
Hue M. La, Ai-Leen Chan, Julien M. D. Legrand, Fernando J. Rossello, Christina G. Gangemi, Antonella Papa et al. GILZ-dependent modulation of mTORC1 regulates spermatogonial maintenance Development 3/16/2018 [PMID: 30126904]
HM La, JA Mäkelä, AL Chan, FJ Rossello, CM Nefzger, JMD Legrand, M De Seram, JM Polo, RM Hobbs Identification of dynamic undifferentiated cell states within the male germline Nat Commun, 2018-07-19;9(1):2819. 7/19/2018 [PMID: 30026551]
Emily E. Bosco, R. James Christie, Rosa Carrasco, Darrin Sabol, Jiping Zha, Karma DaCosta et al. Preclinical evaluation of a GFRA1 targeted antibody-drug conjugate in breast cancer Oncotarget 5/1/2018 [PMID: 29796165]
S Nencini, M Ringuet, DH Kim, C Greenhill, JJ Ivanusic Gdnf, Neurturin and Artemin Activate and Sensitize Bone Afferent Neurons and Contribute To Inflammatory Bone Pain J. Neurosci., 2018-04-30;0(0):. 4/30/2018 [PMID: 29712778]
BA Niedenberg, CB Geyer Advanced immunostaining approaches to study early male germ cell development Stem Cell Res, 2018-02-09;0(0):. 2018-02-09 [PMID: 29475796] (IHC-Fr, Mouse)	IHC-Fr	Mouse
A Kurita-Suz, Y Kamo, C Uchida, K Tanemura, K Hara, T Uchida Prolyl isomerase Pin1 is required sperm production by promoting mitosis progression of spermatogonial stem cells Biochem. Biophys. Res. Commun., 2018-02-10;0(0):. 2018-02-10 [PMID: 29432730] (Immunochromatography, Mouse)	Immunochromatography	Mouse
JC Arnold, MA Cantu, EA Kasanga, VA Nejtek, EV Papa, N Bugnariu, MF Salvatore Aging-related limit of exercise efficacy on motor decline PLoS ONE, 2017-11-27;12(11):e0188538. 2017-11-27 [PMID: 29176896] (Western Blot, Rat)	Western Blot	Rat
Dai MS, Hall SJ, Vantangoli Policelli MM et al. Spontaneous testicular atrophy occurs despite normal spermatogonial proliferation in a Tp53 knockout rat Andrology 8/22/2017 [PMID: 28834365]
S Schaller, D Buttigieg, A Alory, A Jacquier, M Barad, M Merchant, D Gentien, P de la Gran, G Haase Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons Proc. Natl. Acad. Sci. U.S.A, 2017-03-07;114(12):E2486-E2493. 2017-03-07 [PMID: 28270618] (Neutralization, Mouse)	Neutralization	Mouse
Kellie S. Agrimson, Jennifer Onken, Debra Mitchell, Traci B. Topping, Hélio Chiarini-Garcia, Cathryn A. Hogarth et al. Characterizing the Spermatogonial Response to Retinoic Acid During the Onset of Spermatogenesis and Following Synchronization in the Neonatal Mouse Testis1 Biology of Reproduction 10/13/2016 [PMID: 27488029]
Hong Soon Kang, Liang-Yu Chen, Kristin Lichti-Kaiser, Grace Liao, Kevin Gerrish, Carl D. Bortner et al. Transcription Factor GLIS3: A New and Critical Regulator of Postnatal Stages of Mouse Spermatogenesis Stem Cells 11/1/2016 [PMID: 27350140]
Michael F. Salvatore, Jennifer Terrebonne, Victoria Fields, Danielle Nodurft, Cori Runfalo, Brian Latimer et al. Initiation of calorie restriction in middle-aged male rats attenuates aging-related motoric decline and bradykinesia without increased striatal dopamine Neurobiology of Aging 1/1/2016 [PMID: 26610387]
Arnold JC, Salvatore MF. Exercise-mediated increase in nigral tyrosine hydroxylase is accompanied by increased nigral GFR-a1 and EAAC1 expression in aging rats. ACS Chem Neurosci. 11/24/2015 [PMID: 26599339]
Jonathan T. Busada, Bryan A. Niedenberger, Ellen K. Velte, Brett D. Keiper, Christopher B. Geyer Mammalian target of rapamycin complex 1 (mTORC1) Is required for mouse spermatogonial differentiation in vivo Developmental Biology 11/1/2015 [PMID: 26254600]
Shelley L. Forrest, Sophie C. Payne, Janet R. Keast, Peregrine B. Osborne Peripheral injury of pelvic visceral sensory nerves alters GFRα (GDNF family receptor alpha) localization in sensory and autonomic pathways of the sacral spinal cord Frontiers in Neuroanatomy 4/10/2015 [PMID: 25914629]
Bye C, Jonsson M, Bjorklund A, Parish C, Thompson L Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors. Proc Natl Acad Sci U S A, 2015-03-09;112(15):E1946-55. 2015-03-09 [PMID: 25775569] (Flow Cytometry, IHC, Mouse, Rat)	Flow Cytometry, IHC	Mouse, Rat
Bryan A. Niedenberger, Jonathan T. Busada, Christopher B. Geyer Marker expression reveals heterogeneity of spermatogonia in the neonatal mouse testis REPRODUCTION 4/1/2015 [PMID: 25737569]
M Curcio, I L Salazar, A R Inácio, E P Duarte, L M T Canzoniero, C B Duarte Brain ischemia downregulates the neuroprotective GDNF-Ret signaling by a calpain-dependent mechanism in cultured hippocampal neurons Cell Death & Disease 2/12/2015 [PMID: 25675305]
Danielle A. Fanslow, Stacey E. Wirt, Jenny C. Barker, Jon P. Connelly, Matthew H. Porteus, Christina Tenenhaus Dann Genome Editing in Mouse Spermatogonial Stem/Progenitor Cells Using Engineered Nucleases PLoS ONE 11/19/2014 [PMID: 25409432]
Mai Shinomura, Kasane Kishi, Ayako Tomita, Miyuri Kawasumi, Hiromi Kanezashi, Yoshiko Kuroda et al. A novel Amh-Treck transgenic mouse line allows toxin-dependent loss of supporting cells in gonads REPRODUCTION 12/1/2014 [PMID: 25212783]
Aloisio G, Nakada Y, Saatcioglu H, Pena C, Baker M, Tarnawa E, Mukherjee J, Manjunath H, Bugde A, Sengupta A, Amatruda J, Cuevas I, Hamra F, Castrillon D PAX7 expression defines germline stem cells in the adult testis. J Clin Invest, 2014-08-18;124(9):3929-44. 2014-08-18 [PMID: 25133429] (IHC-P, Mouse)	IHC-P	Mouse
Chakraborty P, Buaas F, Sharma M, Snyder E, de Rooij D, Braun R LIN28A marks the spermatogonial progenitor population and regulates its cyclic expansion. Stem Cells, 2014-04-01;32(4):860-73. 2014-04-01 [PMID: 24715688] (IHC, Mouse)	IHC	Mouse
Shelley L. Forrest, Peregrine B. Osborne, Janet R. Keast Characterization of bladder sensory neurons in the context of myelination, receptors for pain modulators, and acute responses to bladder inflammation Frontiers in Neuroscience 11/7/2013 [PMID: 24223534]
Yueh-Chiang Hu, Dirk G. de Rooij, David C. Page Tumor suppressor gene Rb is required for self-renewal of spermatogonial stem cells in mice Proceedings of the National Academy of Sciences 7/30/2013 [PMID: 23858447]
Euteneuer S, Yang K, Chavez E, Leichtle A, Loers G, Olshansky A, Pak K, Schachner M, Ryan A Glial cell line-derived neurotrophic factor (GDNF) induces neuritogenesis in the cochlear spiral ganglion via neural cell adhesion molecule (NCAM). Mol Cell Neurosci, 2012-12-20;54(0):30-43. 2012-12-20 [PMID: 23262364] (Western Blot, Rat)	Western Blot	Rat
Hitomi Suzuki, Christina Tenenhaus Dann, Aleksandar Rajkovic Generation of a germ cell-specific mouse transgenic CHERRY reporter, Sohlh1-mCherryFlag genesis 1/1/2013 [PMID: 22965810]
Meredith J. Goertz, Zhuoru Wu, Teresa D. Gallardo, F. Kent Hamra, Diego H. Castrillon Foxo1 is required in mouse spermatogonial stem cells for their maintenance and the initiation of spermatogenesis Journal of Clinical Investigation 9/1/2011 [PMID: 21865646]
Snyder EM, Small C, Griswold MD Retinoic acid availability drives the asynchronous initiation of spermatogonial differentiation in the mouse. Biol. Reprod., 2010-07-21;83(5):783-90. 2010-07-21 [PMID: 20650878] (IHC-P, Mouse)	IHC-P	Mouse
Janet R. Keast, Shelley L. Forrest, Peregrine B. Osborne Sciatic nerve injury in adult rats causes distinct changes in the central projections of sensory neurons expressing different glial cell line-derived neurotrophic factor family receptors The Journal of Comparative Neurology 8/1/2010 [PMID: 20533358]
Masashi Yamaji, Takashi Tanaka, Mayo Shigeta, Shinichiro Chuma, Yumiko Saga, Mitinori Saitou Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3 REPRODUCTION 2/1/2010 [PMID: 19861488]
Suzuki H, Sada A, Yoshida S, Saga Y The heterogeneity of spermatogonia is revealed by their topology and expression of marker proteins including the germ cell-specific proteins Nanos2 and Nanos3. Dev. Biol., 2009-10-08;336(2):222-31. 2009-10-08 [PMID: 19818747] (ICC, Mouse)	ICC	Mouse
Linher K, Wu D, Li J Glial cell line-derived neurotrophic factor: an intraovarian factor that enhances oocyte developmental competence in vitro. Endocrinology, 2007-05-31;148(9):4292-301. 2007-05-31 [PMID: 17540724] (Neutralization, Western Blot, Porcine)	Neutralization, Western Blot	Porcine
Taylor AR, Gifondorwa DJ, Newbern JM, Robinson MB, Strupe JL, Prevette D, Oppenheim RW, Milligan CE Astrocyte and muscle-derived secreted factors differentially regulate motoneuron survival. J. Neurosci., 2007-01-17;27(3):634-44. 2007-01-17 [PMID: 17234595] (Neutralization, Chicken)	Neutralization	Chicken
Igarashi Y, Aita M, Suzuki A, Nandasena T, Kawano Y, Nozawa-Inoue K, Maeda T Involvement of GDNF and its receptors in the maturation of the periodontal Ruffini endings. Neurosci. Lett., 2006-12-18;412(3):222-6. 2006-12-18 [PMID: 17178438] (IHC, Rat)	IHC	Rat
Malin SA, Molliver DC, Koerber HR, Cornuet P, Frye R, Albers KM, Davis BM Glial cell line-derived neurotrophic factor family members sensitize nociceptors in vitro and produce thermal hyperalgesia in vivo. J. Neurosci., 2006-08-16;26(33):8588-99. 2006-08-16 [PMID: 16914685] (ICC, IHC-Fr, Mouse)	ICC, IHC-Fr	Mouse
Wanigasekara Y, Keast JR Nerve growth factor, glial cell line-derived neurotrophic factor and neurturin prevent semaphorin 3A-mediated growth cone collapse in adult sensory neurons. Neuroscience, 2006-07-28;142(2):369-79. 2006-07-28 [PMID: 16876331] (ICC, Rat)	ICC	Rat
Lee CS, Tee LY, Dusenbery S, Takata T, Golden JP, Pierchala BA, Gottlieb DI, Johnson EM, Choi DW, Snider BJ Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells. Exp. Neurol., 2005-01-01;191(1):65-76. 2005-01-01 [PMID: 15589513] (ICC, Mouse)	ICC	Mouse
Show All 71 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
	4 reviewed by: Verified Customer	IF	Mouse	01/08/2015	View Summary Application Immunofluorescence Sample Tested See PMID 23012458 Species Mouse
	4 reviewed by: Verified Customer	IF	Mouse	01/08/2015	View Summary Application Immunofluorescence Sample Tested See PMID 22711565 Species Mouse
Enlarge	5 reviewed by: Verified Customer	IF	Rat	12/18/2014	View Summary Application Immunofluorescence Sample Tested Recombinant rat GFR alpha-1 expressed in 293 cells Species Rat
	5 reviewed by: Verified Customer	IP	Rat	12/18/2014	View Summary Application Immunoprecipitation Sample Tested Rat GFR alpha-1 expressed in 293 cells Species Rat
	3 reviewed by: Verified Customer	IHC-Fr	Mouse	12/18/2014	View Summary Application Immunohistochemistry-Frozen Sample Tested PFA-fixed cryosections of mouse brain Species Mouse
	5 reviewed by: Verified Customer	IF	Mouse	12/18/2014	View Summary Application Immunofluorescence Sample Tested Hippocampal neurons Species Mouse
	5 reviewed by: Verified Customer	WB	Rat	12/18/2014	View Summary Application Western Blot Sample Tested Recombinant rat GFR alpha-1 expressed in 293 cells Species Rat
	5 reviewed by: Verified Customer	WB	Mouse	12/18/2014	View Summary Application Western Blot Sample Tested Hippocampal neurons Species Mouse

Array AF560

• GFR alpha-1/GDNF R alpha-1 Antibodies
• GFR alpha-1/GDNF R alpha-1 ELISA Kits
• GFR alpha-1/GDNF R alpha-1 Lysates
• GFR alpha-1/GDNF R alpha-1 Proteins
• GFR alpha-1/GDNF R alpha-1 Proteins and Enzymes