GATA-3 Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

GATA-3 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. It is widely expressed in mesodermal- and endodermal-derived tissues. GATA-3 has been shown to be an essential regulator for immune cell function, sympathetic neuron development and the maintenance of the differentiated state in epithelial cells.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 5 confirmed species: Human, Mouse, Rat, Primate - Cholrocebus pygerythrus (Vervet Monkey), Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque).

We have publications tested in 6 applications: ChIP, Flow Cytometry, ICC, IHC, IHC-P, Western Blot.

Showing Publications 1 - 10 of 41. Show All 41 Publications. Collapse Publications.

Publications using AF2605	Applications	Species
Yamamoto, S;Matsui, K;Kinoshita, Y;Hiroshi Sasaki, ;Sekine, H;Saito, Y;Nakayama, Y;Kume, H;Kimura, T;Yokoo, T;Kobayashi, E; Successful reconstruction of the rat ureter by a syngeneic collagen tube with a cardiomyocyte sheet Regenerative therapy 2023-12-01 [PMID: 37868722] (IHC, Rat)	IHC	Rat
Yu, L;Logsdon, D;Pinzon-Arteaga, CA;Duan, J;Ezashi, T;Wei, Y;Ribeiro Orsi, AE;Oura, S;Liu, L;Wang, L;Liu, K;Ding, X;Zhan, L;Zhang, J;Nahar, A;Stobbe, C;Katz-Jaffe, M;Schoolcraft, WB;Tan, T;Hon, GC;Yuan, Y;Wu, J; Large-scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal cross talk Cell stem cell 2023-09-07 [PMID: 37683605] (ICC, Human)	ICC	Human
Agathe Lermant, Gwenaëlle Rabussier, Henriëtte L. Lanz, Lindsay Davidson, Iain M. Porter, Colin E. Murdoch Development of a human iPSC-derived placental barrier-on-chip model iScience 7/21/2023 [PMID: 37534160]
J Li, Q Zhu, J Cao, Y Liu, Y Lu, Y Sun, Q Li, Y Huang, S Shang, X Bian, C Li, L Zhang, Y Wang, Y Nie, J Fu, W Li, MA Mazid, Y Jiang, W Jia, X Wang, Y Sun, MA Esteban, Q Sun, F Zhou, Z Liu Cynomolgus monkey embryo model captures gastrulation and early pregnancy Cell Stem Cell, 2023-04-06;30(4):362-377.e7. 2023-04-06 [PMID: 37028403] (IHC, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque))	IHC	Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Jessica M. Vanslambrouck, Sean B. Wilson, Ker Sin Tan, Ella Groenewegen, Rajeev Rudraraju, Jessica Neil et al. Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids Nature Communications 10/8/2022 [PMID: 36209212]
K Hiratsuka, T Miyoshi, KT Kroll, NR Gupta, MT Valerius, T Ferrante, M Yamashita, JA Lewis, R Morizane Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery Science Advances, 2022-09-21;8(38):eabq0866. 2022-09-21 [PMID: 36129975] (IHC, Human)	IHC	Human
M Ohgushi, N Taniyama, A Vandenbon, M Eiraku Delamination of trophoblast-like syncytia from the amniotic ectodermal analogue in human primed embryonic stem cell-based differentiation model Cell Reports, 2022-06-21;39(12):110973. 2022-06-21 [PMID: 35732132] (Flow Cytometry, ICC, Human)	Flow Cytometry, ICC	Human
Jessica M. Vanslambrouck, Sean B. Wilson, Ker Sin Tan, Ella Groenewegen, Rajeev Rudraraju, Jessica Neil et al. Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids bioRxiv 4/15/2023 [PMID: 35665006]
Lawrence M, Elhendawi M, Morlock M et al. Human iPSC-derived renal organoids engineered to report oxidative stress can predict drug-induced toxicity iScience 3/1/2022 [PMID: 35243244]
Yatsumu Saito, Naoto Matsumoto, Shuichiro Yamanaka, Takashi Yokoo, Eiji Kobayashi Beneficial Impact of Interspecies Chimeric Renal Organoids Against a Xenogeneic Immune Response Frontiers in Immunology 2/15/2022 [PMID: 35242145]
Julie Bejoy, Eddie Spencer Qian, Lauren Elizabeth Woodard Accelerated protocol for the differentiation of podocytes from human pluripotent stem cells STAR Protocols 12/1/2021 [PMID: 34746862]
Meng Zhu, Marta Shahbazi, Angel Martin, Chuanxin Zhang, Berna Sozen, Mate Borsos et al. Human embryo polarization requires PLC signaling to mediate trophectoderm specification eLife 9/27/2021 [PMID: 34569938]
D Meisterman, A Bruneau, S Loubersac, A Reignier, J Firmin, V François-C, S Kilens, Y Lelièvre, J Lammers, M Feyeux, P Hulin, S Nedellec, B Bretin, G Castel, N Allègre, S Covin, A Bihouée, M Soumillon, T Mikkelsen, P Barrière, C Chazaud, J Chappell, V Pasque, J Bourdon, T Fréour, L David Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification Cell Stem Cell, 2021-05-17;0(0):. 2021-05-17 [PMID: 34004179] (IHC, Human)	IHC	Human
SE Howden, SB Wilson, E Groenewege, L Starks, TA Forbes, KS Tan, JM Vanslambro, EM Holloway, YH Chen, S Jain, JR Spence, MH Little Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk Cell Stem Cell, 2020-12-29;0(0):. 2020-12-29 [PMID: 33378647] (IHC, Human)	IHC	Human
K Uchimura, H Wu, Y Yoshimura, BD Humphreys Human Pluripotent Stem Cell-Derived Kidney Organoids with Improved Collecting Duct Maturation and Injury Modeling Cell Reports, 2020-12-15;33(11):108514. 2020-12-15 [PMID: 33326782] (IHC, Human)	IHC	Human
MN Shahbazi, T Wang, X Tao, BAT Weatherbee, L Sun, Y Zhan, L Keller, GD Smith, A Pellicer, RT Scott, E Seli, M Zernicka-G Developmental potential of aneuploid human embryos cultured beyond implantation Nat Commun, 2020-08-10;11(1):3987. 2020-08-10 [PMID: 32778678] (ICC, IHC, Human)	ICC, IHC	Human
AI Yu, L Zhao, KA Eaton, S Ho, J Chen, S Poe, J Becker, A Gonzalez, D McKinstry, M Hasso, J Mendoza-Ca, J Whitfield, C Koumpouras, PD Schloss, EC Martens, GY Chen Gut Microbiota Modulate CD8�T Cell Responses to Influence Colitis-Associated Tumorigenesis Cell Rep, 2020-04-07;31(1):107471. 2020-04-07 [PMID: 32268087] (ICC, Human)	ICC	Human
Z Tan, A Rak-Raszew, I Skovorodki, SJ Vainio Mouse Embryonic Stem Cell-Derived Ureteric Bud Progenitors Induce Nephrogenesis Cells, 2020-01-31;9(2):. 2020-01-31 [PMID: 32023845] (IHC, Mouse)	IHC	Mouse
Chao Li, Xiang Li, Zhenghong Bi, Ken Sugino, Guangqin Wang, Tong Zhu et al. Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages eLife 1/8/2020 [PMID: 31913118]
S Nomura, H Takahashi, J Suzuki, M Kuwahara, M Yamashita, T Sawasaki Pyrrothiogatain acts as an inhibitor of GATA family proteins and inhibits Th2 cell differentiation in vitro Sci Rep, 2019-11-22;9(1):17335. 2019-11-22 [PMID: 31758034] (ChIP, Mouse)	ChIP	Mouse
Martina Dvorakova, Iva Macova, Romana Bohuslavova, Miroslava Anderova, Bernd Fritzsch, Gabriela Pavlinkova Early ear neuronal development, but not olfactory or lens development, can proceed without SOX2 Developmental Biology 1/1/2020 [PMID: 31526806]
Vanslambrouck J M, Wilson S B et al. A Toolbox to Characterize Human Induced Pluripotent Stem Cell-Derived Kidney Cell Types and Organoids. J Am Soc Nephrol 1/10/2019 [PMID: 31492807]
Alexander N. Combes, Belinda Phipson, Kynan T. Lawlor, Aude Dorison, Ralph Patrick, Luke Zappia et al. Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk Development 6/15/2019 [PMID: 31118232]
Sara E Howden, Jessica M Vanslambrouck, Sean B Wilson, Ker Sin Tan, Melissa H Little Reporter‐based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation EMBO reports 4/1/2019 [PMID: 30858339]
F Schutgens, MB Rookmaaker, T Margaritis, A Rios, C Ammerlaan, J Jansen, L Gijzen, M Vormann, A Vonk, M Viveen, FY Yengej, S Derakhshan, KM de Winter-, B Artegiani, R van Boxtel, E Cuppen, APA Hendrickx, MM van den He, E Heitzer, H Lanz, J Beekman, JL Murk, R Masereeuw, F Holstege, J Drost, MC Verhaar, H Clevers Tubuloids derived from human adult kidney and urine for personalized disease modeling Nat. Biotechnol., 2019-03-04;37(3):303-313. 2019-03-04 [PMID: 30833775] (IHC, Human)	IHC	Human
B Phipson, PX Er, AN Combes, TA Forbes, SE Howden, L Zappia, HJ Yen, KT Lawlor, LJ Hale, J Sun, E Wolvetang, M Takasato, A Oshlack, MH Little Evaluation of variability in human kidney organoids Nat. Methods, 2018-12-20;16(1):79-87. 2018-12-20 [PMID: 30573816] (IHC, Mouse)	IHC	Mouse
MY Turco, L Gardner, RG Kay, RS Hamilton, M Prater, MS Hollinshea, A McWhinnie, L Esposito, R Fernando, H Skelton, F Reimann, FM Gribble, A Sharkey, SGE Marsh, S O'Rahilly, M Hemberger, GJ Burton, A Moffett Trophoblast organoids as a model for maternal-fetal interactions during human placentation Nature, 2018-11-28;0(0):. 2018-11-28 [PMID: 30487605] (IHC, Human)	IHC	Human
Nils O. Lindström, Tracy Tran, Jinjin Guo, Elisabeth Rutledge, Riana K. Parvez, Matthew E. Thornton et al. Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning Journal of the American Society of Nephrology 3/1/2018 [PMID: 29449451]
P Shahi, CY Wang, J Chou, C Hagerling, H Gonzalez V, A Ruderisch, Y Yu, MD Lai, Z Werb GATA3 targets semaphorin 3B in mammary epithelial cells to suppress breast cancer progression and metastasis Oncogene, 2017-06-05;0(0):. 2017-06-05 [PMID: 28581515] (Western Blot, Human)	Western Blot	Human
Koji Nishimura, Teppei Noda, Alain Dabdoub Dynamic Expression of Sox2, Gata3, and Prox1 during Primary Auditory Neuron Development in the Mammalian Cochlea PLOS ONE 1/24/2017 [PMID: 28118374]
Minoru Takasato, Pei X Er, Han S Chiu, Melissa H Little Generation of kidney organoids from human pluripotent stem cells Nature Protocols 9/1/2016 [PMID: 27560173]
Takasato M, Er P, Chiu H, Maier B, Baillie G, Ferguson C, Parton R, Wolvetang E, Roost M, Chuva de Sousa Lopes S, Little M Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature, 2015-10-07;526(7574):564-8. 2015-10-07 [PMID: 26444236] (IHC, Human)	IHC	Human
Tabata T, Petitt M, Zydek M, Fang-Hoover J, Larocque N, Tsuge M, Gormley M, Kauvar L, Pereira L Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta. J Virol, 2015-03-04;89(9):5134-47. 2015-03-04 [PMID: 25741001] (IHC-P, Human)	IHC-P	Human
Koehler KR, Hashino E. 3D mouse embryonic stem cell culture for generating inner ear organoids. Nat Protoc 6/1/2014 [PMID: 24784820]
Yu , Wei-Ming, Appler , Jessica, Kim , Ye-Hyun, Nishitani , Allison, Holt , Jeffrey, Goodrich , Lisa V A Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing. Elife, 2013-12-10;2(0):e01341. 2013-12-10 [PMID: 24327562] (IHC, Mouse)	IHC	Mouse
Rafael Nunez-Nateras, Erik P. Castle, Cheryl A. Protheroe, Melissa L. Stanton, Tolgay I. Ocal, Erin N. Ferrigni et al. Predicting response to bacillus Calmette-Guérin (BCG) in patients with carcinoma in situ of the bladder Urologic Oncology: Seminars and Original Investigations 1/1/2014 [PMID: 24055426]
Jessica M. Appler, Cindy C. Lu, Noah R. Druckenbrod, Wei-Ming Yu, Edmund J. Koundakjian, Lisa V. Goodrich Gata3 Is a Critical Regulator of Cochlear Wiring The Journal of Neuroscience 2/20/2013 [PMID: 23426694]
Alexandra Sufit, Andrew M. Donson, Diane K. Birks, Jeffrey A. Knipstein, Laura Z. Fenton, Paul Jedlicka et al. Diffuse intrinsic pontine tumors: a study of primitive neuroectodermal tumors versus the more common diffuse intrinsic pontine gliomas Journal of Neurosurgery: Pediatrics 8/1/2012 [PMID: 22747092]
Pellegrino MJ, Parrish DC, Zigmond RE, Habecker BA Cytokines inhibit norepinephrine transporter expression by decreasing Hand2. Mol. Cell. Neurosci., 2011-01-15;46(3):671-80. 2011-01-15 [PMID: 21241805] (Western Blot, Human)	Western Blot	Human
Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, Minami T Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells. J. Biol. Chem., 2009-08-12;284(42):29109-24. 2009-08-12 [PMID: 19674970] (ICC, Western Blot, Human, Primate - Cholrocebus pygerythrus (Vervet Monkey))	ICC, Western Blot	Human, Primate - Cholrocebus pygerythrus (Vervet Monkey)
Ren Y, Lu L, Guo TB, Qiu J, Yang Y, Liu A, Zhang JZ Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis. J. Immunol., 2008-07-15;181(2):1491-8. 2008-07-15 [PMID: 18606704] (Western Blot, Mouse)	Western Blot	Mouse
Show All 41 Publications. Collapse Publications.

Array AF2605

• GATA-3 Antibodies
• GATA-3 ELISA Kits
• GATA-3 Lysates
• GATA-3 Proteins