GADD153/CHOP Antibody (9C8) [HRP]

GADD153, also known as CHOP or DDIT3, is as a growth arrest and DNA damage-inducible gene that encodes a C/EBP-related nuclear protein. This protein functions as a transcriptional inhibitor by forming heterodimers with C/EBP (CCAAT/enhancer-binding protein) and LAP (liver activator protein), and preventing their DNA binding activity. Under normal growth conditions GADD153 is dormant; however it is highly unregulated during cellular stress caused by toxins, metabolic inhibitors and nutrient deprivation. GADD153 is present in the cytosol under nonstressed conditions and then accumulates in the nucleus once it is induced by stress.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 1 application: ELISA.

Showing Publication 1 - 1 of 1.

Publication using NB600-1335H	Applications	Species
Cueno ME, Ochiai K Gingival Periodontal Disease (PD) Level-Butyric Acid Affects the Systemic Blood and Brain Organ: Insights Into the Systemic Inflammation of Periodontal Disease Front Immunol Jun 4 2018 [PMID: 29915575] (ELISA, Rat) Front Immunol. 2019-04-15 [PMID: 29915575] (ELISA, Rat) Details: Citation using the HRP form of this antibody.	ELISA	Rat

Array NB600-1335H

• GADD153/CHOP Antibodies
• GADD153/CHOP ELISA Kits
• GADD153/CHOP Lysate
• GADD153/CHOP Proteins