GADD153/CHOP Antibody (9C8) [Biotin]

GADD153, also known as CHOP or DDIT3, is as a growth arrest and DNA damage-inducible gene that encodes a C/EBP-related nuclear protein. This protein functions as a transcriptional inhibitor by forming heterodimers with C/EBP (CCAAT/enhancer-binding protein) and LAP (liver activator protein), and preventing their DNA binding activity. Under normal growth conditions GADD153 is dormant; however it is highly unregulated during cellular stress caused by toxins, metabolic inhibitors and nutrient deprivation. GADD153 is present in the cytosol under nonstressed conditions and then accumulates in the nucleus once it is induced by stress.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IP, WB.

Showing Publications 1 - 2 of 2.

Publications using NB600-1335B	Applications	Species
Dolatabadi S, Jonasson E, Andersson L Et al. FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma Front Oncol 2022-02-21 [PMID: 35186752] (IP, Human) Details: Citation using the Biotin version of this antibody.	IP	Human
Lind�n M, Vannas C, �sterlund T et al. FET fusion oncoproteins interact with BRD4 and SWI/SNF chromatin remodelling complex subtypes in sarcoma Molecular Oncology 2022-07-01 [PMID: 35182012] (WB)	WB

Array NB600-1335B

• GADD153/CHOP Antibodies
• GADD153/CHOP ELISA Kits
• GADD153/CHOP Lysate
• GADD153/CHOP Proteins