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FPR1 Antibody (350418)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
350418
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3744U-100UG
Alexa Fluor 405
FAB3744V-100UG
Alexa Fluor 488
FAB3744G-100UG
Alexa Fluor 532
FAB3744X
Alexa Fluor 594
FAB3744T-100UG
Alexa Fluor 647
FAB3744R-100UG
Alexa Fluor 700
FAB3744N-100UG
Alexa Fluor 750
FAB3744S-100UG
Allophycocyanin
FAB3744A
Allophycocyanin/Cy7
FAB3744APCCY7
Biotin
FAB3744B
CoraFluor 1
FAB3744CL1
DyLight 350
FAB3744D
DyLight 405
FAB3744E
DyLight 488
FAB3744K
DyLight 550
FAB3744L
DyLight 594
FAB3744M
DyLight 650
FAB3744W
DyLight 680
FAB3744Y
DyLight 755
FAB3744Z
HRP
FAB3744H
Janelia Fluor 525
FAB3744JF525
Janelia Fluor 549
FAB3744I
Janelia Fluor 646
FAB3744J
Janelia Fluor 669
FAB3744JF669
PE/Atto594
FAB3744PEATT594
PE/Cy5.5
FAB3744PECY55
PE/Cy7
FAB3744PECY7
PerCP
FAB3744C
Phycoerythrin
FAB3744P
mFluor Violet 450 SE
FAB3744MFV450
mFluor Violet 500 SE
FAB3744MFV500
mFluor Violet 610 SE
FAB3744MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
FAB3744A
Carrier Free
FAB3744P
Carrier Free
MAB3744-SP
Carrier Free
FAB3744V-100UG
Carrier Free
FAB3744U-100UG
Carrier Free
FAB3744T-100UG
Carrier Free
FAB3744S-100UG
Carrier Free
FAB3744R-100UG
Carrier Free
FAB3744N-100UG
Carrier Free
FAB3744G-100UG
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FPR1 Antibody (350418) Summary

Immunogen
HEK293 human embryonic kidney cell line transfected with human FPR1
Met1-Lys350
Accession # NP_002020
Specificity
Detects human FPR1. Stains human FPR1-transfected cells but not irrelevant transfectants.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
FPR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
Publications
Read Publications using
MAB3744 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FPR1 Antibody (350418)

  • fMet-Leu-Phe receptor
  • fMLF-R
  • fMLP receptor
  • FMLP
  • formyl peptide receptor 1
  • FPR1
  • FPRfMet-Leu-Phe receptor
  • N-formyl peptide receptor
  • N-formylpeptide chemoattractant receptor

Background

FPR1, FPRL1, and FPRL2 constitute a group of 7-transmembrane segment chemotactic receptors that are expressed on phagocytes. FPR1 binding of bacterial N‑formyl‑methionyl peptides draws neutrophils to sites of infection and promotes degranulation. Human and mouse FPR1 share 73% amino acid sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for FPR1 Antibody (MAB3744)(9)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: Flow Cytometry, ICC.


Filter By Application
Flow Cytometry
(4)
ICC
(2)
All Applications
Filter By Species
Human
(6)
All Species
Showing Publications 1 - 9 of 9.
Publications using MAB3744 Applications Species
L Busch, Z Al Taleb, YL Tsai, VTT Nguyen, Q Lu, CV Synatschke, K Endres, B Bufe Amyloid beta and its naturally occurring N-terminal variants are potent activators of human and mouse formyl peptide receptor 1 The Journal of Biological Chemistry, 2022-10-27;0(0):102642. 2022-10-27 [PMID: 36309087] (ICC, Human) ICC Human
Kiyoshi Itagaki, Elzbieta Kaczmarek, Woon Yong Kwon, Li Chen, Barbora Vlková, Quanzhi Zhang et al. Formyl Peptide Receptor-1 Blockade Prevents Receptor Regulation by Mitochondrial Danger-Associated Molecular Patterns and Preserves Neutrophil Function After Trauma Critical Care Medicine 2/25/2020 [PMID: 31939811]
HY Lee, YS Jeong, M Lee, HS Kweon, YH Huh, JS Park, JE Hwang, K Kim, YS Bae Intracellular formyl peptide receptor regulates na�ve CD4 T cell migration Biochem. Biophys. Res. Commun., 2018-02-08;0(0):. 2018-02-08 [PMID: 29427663] (Flow Cytometry, Human) Flow Cytometry Human
Bufe B, Schumann T, Kappl R, Bogeski I, Kummerow C, Podgorska M, Smola S, Hoth M, Zufall F Recognition of bacterial signal peptides by mammalian formyl peptide receptors: a new mechanism for sensing pathogens. J Biol Chem, 2015-01-20;290(12):7369-87. 2015-01-20 [PMID: 25605714] (ICC, Human) ICC Human
Robin Butler, David Hornigold, Ling Huang, Catherine Huntington, Tim London, Janette Dillon et al. Use of the Site-Specific Retargeting Jump-In Platform Cell Line to Support Biologic Drug Discovery J Biomol Screen 4/1/2015 [PMID: 25534831]
Julie A Douthwaite, Sudharsan Sridharan, Catherine Huntington, Jayne Hammersley, Rose Marwood, Jonna K Hakulinen et al. Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1 mAbs 1/2/2015 [PMID: 25484051]
Prevete N, Liotti F, Visciano C, Marone G, Melillo R, de Paulis A The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis. Oncogene, 2014-09-29;34(29):3826-38. 2014-09-29 [PMID: 25263443] (Flow Cytometry, Human) Flow Cytometry Human
Mintz R, Garty BZ, Meshel T, Marcus N, Katanov C, Cohen-Hillel E, Ben-Baruch A Reduced expression of chemoattractant receptors by polymorphonuclear leukocytes in Hyper IgE Syndrome patients. Immunol. Lett., 2009-12-11;130(1):97-106. 2009-12-11 [PMID: 20005258] (Flow Cytometry, Human) Flow Cytometry Human
Ishmael SS, MacGlashan DW Syk expression in peripheral blood leukocytes, CD34+ progenitors, and CD34-derived basophils. J. Leukoc. Biol., 2009-11-04;87(2):291-300. 2009-11-04 [PMID: 19889729] (Flow Cytometry, Human) Flow Cytometry Human

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Bioinformatics

Gene Symbol FPR1
Uniprot