FPR1 Antibody (350418) [Phycoerythrin]

Images

 
Human monocytes were stained with Mouse Anti-Human FPR1 PE-conjugated Monoclonal Antibody (Catalog # FAB3744P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
350418
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

FPR1 Antibody (350418) [Phycoerythrin] Summary

Immunogen
HEK293 human embryonic kidney cell line transfected with human FPR1
Met1-Lys350
Accession # NP_002020
Specificity
Detects human FPR1. Stains human FPR1-transfected cells but not irrelevant transfectants.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
FPR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Reviewed Applications
Read 1 Review rated 4
using
FAB3744P in the following application:

Publications
Read Publications using
FAB3744P in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FPR1 Antibody (350418) [Phycoerythrin]

  • fMet-Leu-Phe receptor
  • fMLF-R
  • fMLP receptor
  • FMLP
  • formyl peptide receptor 1
  • FPR1
  • FPRfMet-Leu-Phe receptor
  • N-formyl peptide receptor
  • N-formylpeptide chemoattractant receptor

Background

FPR1, FPRL1, and FPRL2 constitute a group of 7-transmembrane segment chemotactic receptors that are expressed on phagocytes. FPR1 binding of bacterial N‑formyl‑methionyl peptides draws neutrophils to sites of infection and promotes degranulation. In addition, a novel chemokine-like molecule, FAM19A4, has also been shown to bind to FPR1.  Human and mouse FPR1 share 73% amino acid sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for FPR1 Antibody (FAB3744P)(6)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: Bioassay, Flow Cytometry.


Filter By Application
Bioassay
(1)
Flow Cytometry
(4)
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Filter By Species
Human
(4)
Mouse
(1)
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Showing Publications 1 - 6 of 6.
Publications using FAB3744P Applications Species
Hennequart, M;Pilley, SE;Labuschagne, CF;Coomes, J;Mervant, L;Driscoll, PC;Legrave, NM;Lee, Y;Kreuzaler, P;Macintyre, B;Panina, Y;Blagih, J;Stevenson, D;Strathdee, D;Schneider-Luftman, D;Gr�nroos, E;Cheung, EC;Yuneva, M;Swanton, C;Vousden, KH; ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis Cell reports 2023-05-26 [PMID: 37245210] (Bioassay, Mouse) Bioassay Mouse
DS Ahmet, HA Basheer, A Salem, D Lu, A Aghamohamm, P Weyerhäuse, A Bordiga, J Almeniawi, S Rashid, PA Cooper, SD Shnyder, V Vinader, K Afarinkia Application of small molecule FPR1 antagonists in the treatment of cancers Sci Rep, 2020-10-14;10(1):17249. 2020-10-14 [PMID: 33057069] (Flow Cytometry, Human) Flow Cytometry Human
Clark GJ et al. New insights into the phenotype of human dendritic cell populations. Clin Transl Immunology 1/1/2016 [PMID: 26900474]
Gemperle C, Schmid M, Herova M, Marti-Jaun J, Wuest S, Loretz C, Hersberger M Regulation of the formyl peptide receptor 1 (FPR1) gene in primary human macrophages. PLoS ONE, 2012-11-21;7(11):e50195. 2012-11-21 [PMID: 23185575] (Flow Cytometry, Human) Flow Cytometry Human
Schneider , Erich H, Weaver , Joseph D, Gaur , Sonia S, Tripathi , Brajendr, Jesaitis , Algirdas, Zelenka , Peggy S, Gao , Ji-Liang, Murphy , Philip M The leukocyte chemotactic receptor FPR1 is functionally expressed on human lens epithelial cells. J Biol Chem, 2012-09-25;287(48):40779-92. 2012-09-25 [PMID: 23012360] (Flow Cytometry, Human) Flow Cytometry Human
McDermott DH, De Ravin SS, Jun HS Severe congenital neutropenia resulting from G6PC3 deficiency with increased neutrophil CXCR4 expression and myelokathexis. Blood, 2010-07-08;116(15):2793-802. 2010-07-08 [PMID: 20616219] (Flow Cytometry, Human) Flow Cytometry Human

Review for FPR1 Antibody (FAB3744P) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using FAB3744P:
Filter by Applications
Flow
(1)
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Filter by Species
Human
(1)
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Images Ratings Applications Species Date Details
  4
reviewed by:
Verified Customer
Flow Human 01/26/2015
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Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 23012360
SpeciesHuman

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FAQs for FPR1 Antibody (FAB3744P) (0)

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Verified Customer
01/26/2015
Application: Flow
Species: Human

Bioinformatics

Gene Symbol FPR1
Uniprot