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FOXO3 [p Ser253] Antibody (SR2309)

Images

 
Immunohistochemistry: FOXO3 [p Ser 253] Antibody (SR2309) [NBP3-21531] - Immunohistochemical analysis of paraffin-embedded human uterus cancer, using NBP3-21531.
Western Blot: FOXO3 [p Ser 253] Antibody (SR2309) [NBP3-21531] - Western blot analysis using NBP3-21531 in MCF-7 cell lysate treated with IGF.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
SR2309
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

FOXO3 [p Ser253] Antibody (SR2309) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human phospho-FOXO3 [Ser253] (Uniprot #: O43524)
Modification
p Ser253
Specificity
Detects endogenous levels of total phospho-FOXO3 [Ser253]
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
FOXO3
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50-1:200
  • Western Blot 1:500-1:2000
Theoretical MW
97 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for FOXO3 [p Ser253] Antibody (SR2309)

  • AF6q21 protein
  • AF6q21
  • DKFZp781A0677
  • FKHRL1
  • FKHRL1MGC31925
  • FKHRL1P2
  • forkhead box O3
  • forkhead box protein O3
  • forkhead homolog (rhabdomyosarcoma) like 1
  • Forkhead in rhabdomyosarcoma-like 1
  • forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1
  • FOXO2
  • FoxO3
  • FOXO3A
  • FOXO3Aforkhead box O3A
  • MGC12739

Background

FOX3 probably functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of the FOXO3 gene with the MLL gene is associated with secondary acute leukemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol FOXO3